Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.
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For glioma, a sweet side to diabetesRepurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastomaInhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A).Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells.Drug combination therapy increases successful drug repositioning.Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2.Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastomaLong noncoding RNA RP11-838N2.4 enhances the cytotoxic effects of temozolomide by inhibiting the functions of miR-10a in glioblastoma cell lines.Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes.Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway.Study protocol of a phase IB/II clinical trial of metformin and chloroquine in patients with IDH1-mutated or IDH2-mutated solid tumoursLithium enhances the antitumour effect of temozolomide against TP53 wild-type glioblastoma cells via NFAT1/FasL signalling.Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells.Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation.Metformin treatment reduces temozolomide resistance of glioblastoma cells.Post-transcriptional regulation of 5'-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients.Research on human glioma stem cells in China.Cdc20 overexpression is involved in temozolomide-resistant glioma cells with epithelial-mesenchymal transition.Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models.Metformin as an anti-cancer agent: actions and mechanisms targeting cancer stem cells.High-Dose Metformin Plus Temozolomide Shows Increased Anti-tumor Effects in Glioblastoma In Vitro and In Vivo Compared with Monotherapy.New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.Potential Strategies Overcoming the Temozolomide Resistance for GlioblastomaDevelopments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of GlioblastomaDrug Repurposing of Metabolic Agents in Malignant Glioma
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P2860
Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@ast
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@en
type
label
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@ast
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@en
prefLabel
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@ast
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@en
P2093
P2860
P356
P1433
P1476
Metformin and temozolomide act ...... em cells in vitro and in vivo.
@en
P2093
Guifang Xie
Hongquan Yu
Liyan Zhao
Yunqian Li
Zhonghua Zhang
P2860
P304
32930-32943
P356
10.18632/ONCOTARGET.5405
P407
P577
2015-09-26T00:00:00Z