p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation. - Wikidata - wikimedia - TriplyDB

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

http://www.wikidata.org/entity/Q36546981

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Paradoxical role of SOX2 in gastric cancer Specification and function of hemogenic endothelium during embryogenesis A gonogenic stimulated transition of mouse embryonic stem cells with enhanced control of diverse differentiation pathways Targeting SOX2 as a Therapeutic Strategy in Glioblastoma Transcriptional control of stem cell fate by E2Fs and pocket proteins Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea Perspectives of gene combinations in phenotype presentation Transcriptomic Effects of the Cell Cycle Regulator LGO in Arabidopsis Sepals p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Human stem cells for craniomaxillofacial reconstruction.Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration.A Histopathological Study of Multi-hormone Producing Proliferative Lesions in Estrogen-induced Rat Pituitary Prolactinoma.SOX9 accelerates ESC differentiation to three germ layer lineages by repressing SOX2 expression through P21 (WAF1/CIP1)Genetic regulation of murine pituitary development.Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis.Transcriptional regulation of Sox2 by the retinoblastoma family of pocket proteins.DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2.Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation.p27Kip1 and p21Cip1 collaborate in the regulation of transcription by recruiting cyclin-Cdk complexes on the promoters of target genes.Loss of p27Kip¹ promotes metaplasia in the pancreas via the regulation of Sox9 expression Attenuation of teratoma formation by p27 overexpression in induced pluripotent stem cells.Initiation of stem cell differentiation involves cell cycle-dependent regulation of developmental genes by Cyclin D The non-canonical functions of p27(Kip1) in normal and tumor biology.Deficiency of the cyclin-dependent kinase inhibitor, CDKN1B, results in overgrowth and neurodevelopmental delay SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary p27(KIP1) loss promotes proliferation and phagocytosis but prevents epithelial-mesenchymal transition in RPE cells after photoreceptor damage.Novel functions for the transcription factor E2F4 in development and disease.Novel function of MDA-9/Syntenin (SDCBP) as a regulator of survival and stemness in glioma stem cells.Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state.Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control.The sox family of transcription factors: versatile regulators of stem and progenitor cell fate.Nervous decision-making: to divide or differentiate.Cell cycle regulation of proliferation versus differentiation in the central nervous system.Can the 'neuron theory' be complemented by a universal mechanism for generic neuronal differentiation.PRMT8 Controls the Pluripotency and Mesodermal Fate of Human Embryonic Stem Cells By Enhancing the PI3K/AKT/SOX2 Axis.Crosstalk between stem cell and cell cycle machineries.p27Kip1, PCAF and PAX5 cooperate in the transcriptional regulation of specific target genes.Formula G1: Cell cycle in the driver's seat of stem cell fate determination.The dark side of SOX2: cancer - a comprehensive overview.RB: An essential player in adult neurogenesis.

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P2860

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

http://www.wikidata.org/entity/Q36546981

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

@ast

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

@en

type

label

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

@ast

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

@en

prefLabel

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

@ast

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation.

@en

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J.STEM.2012.09.014

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P1476

p27(Kip1) directly represses Sox2 during embryonic stem cell differentiation

@en

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Ander Matheu

http://www.w3.org/2001/XMLSchema#string

Carmen Carneiro

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Cian J Lynch

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Gloria Martínez

http://www.w3.org/2001/XMLSchema#string

Han Li

http://www.w3.org/2001/XMLSchema#string

Marta Cañamero

http://www.w3.org/2001/XMLSchema#string

Robin Lovell-Badge

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P2860

A GRFa2/Prop1/stem (GPS) cell niche in the pituitary

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival

Multipotent cell lineages in early mouse development depend on SOX2 function

Mutations within Sox2/SOX2 are associated with abnormalities in the hypothalamo-pituitary-gonadal axis in mice and humans

SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland.

SOX2 is a dose-dependent regulator of retinal neural progenitor competence

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells

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845-852

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10.1016/J.STEM.2012.09.014

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6

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Aranzazu Villasante

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233875544

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23217425

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3549496

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