RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter.
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Protein phosphatase X interacts with c-Rel and stimulates c-Rel/nuclear factor kappaB activityInteraction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase.Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cellsTranscriptional Activation of the Interleukin-2 Promoter by Hepatitis C Virus Core ProteinHematopoietic progenitor kinase 1 is a component of transforming growth factor beta-induced c-Jun N-terminal kinase signaling cascadeUnifying concepts in CD28, ICOS and CTLA4 co-receptor signallingIdentification of an upstream enhancer within a functional promoter of the human leukemia inhibitory factor receptor gene and its alternative promoter usageRole of transcriptional repressor ICER in cyclic AMP-mediated attenuation of cytokine gene expression in human thymocytesInteraction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activationNF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responsesA single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator (ICOS)ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation.Cell-intrinsic NF-κB activation is critical for the development of natural regulatory T cells in mice.Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locusThe role of the FOXP3 transcription factor in the immune regulation of allergic asthma.Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors.Irbesartan inhibits human T-lymphocyte activation through downregulation of activator protein-1.NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-thetaSignal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element.Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508.A dynamic assembly of diverse transcription factors integrates activation and cell-type information for interleukin 2 gene regulation.NF-κB: roles and regulation in different CD4(+) T-cell subsets.Involvement of Jun and Rel proteins in up-regulation of interleukin-4 gene activity by the T cell accessory molecule CD28.Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappaB and a 90-kDa phosphoprotein coactivator.Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3.Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment.Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta.Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 geneRequirements for interleukin 2 promoter transactivation by the Tax protein of human T-cell leukemia virus type 1.Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding.CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites.Transcriptional regulation of the interleukin-2 gene in normal human peripheral blood T cells. Convergence of costimulatory signals and differences from transformed T cells.CD25high T cells with a prolonged survival inhibit development of diabetes.Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2.Low levels of NF-κB/p65 mark anergic CD4+ T cells and correlate with disease severity in sarcoidosis.Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-kappaB, and AP-1 induction.Enhanced acute responses in an experimental exposure model to biomass smoke inhalation in chronic obstructive pulmonary disease.
P2860
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P2860
RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
RelA is a potent transcription ...... in the interleukin 2 promoter.
@ast
RelA is a potent transcription ...... in the interleukin 2 promoter.
@en
type
label
RelA is a potent transcription ...... in the interleukin 2 promoter.
@ast
RelA is a potent transcription ...... in the interleukin 2 promoter.
@en
prefLabel
RelA is a potent transcription ...... in the interleukin 2 promoter.
@ast
RelA is a potent transcription ...... in the interleukin 2 promoter.
@en
P2093
P2860
P356
P1476
RelA is a potent transcription ...... in the interleukin 2 promoter.
@en
P2093
P2860
P304
P356
10.1128/MCB.15.8.4260
P407
P577
1995-08-01T00:00:00Z