Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells.
about
The Natural Occurring Compounds Targeting Endoplasmic Reticulum StressTargeting autophagy to sensitive glioma to temozolomide treatmentMmu-miR-125b overexpression suppresses NO production in activated macrophages by targeting eEF2K and CCNA2.Transforming growth factor-β1 up-regulates connexin43 expression in human granulosa cellsInhibition of eEF-2 kinase sensitizes human nasopharyngeal carcinoma cells to lapatinib-induced apoptosis through the Src and Erk pathways.Therapeutic targeting of autophagy in disease: biology and pharmacology.Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation.Integrative bioinformatics and proteomics-based discovery of an eEF2K inhibitor (cefatrizine) with ER stress modulation in breast cancer cells.Silencing of EEF2K (eukaryotic elongation factor-2 kinase) reveals AMPK-ULK1-dependent autophagy in colon cancer cells.Inhibition of elongation factor-2 kinase augments the antitumor activity of Temozolomide against glioma.Eukaryotic elongation factor-2 kinase (eEF2K): a potential therapeutic target in cancer.Regulated stability of eukaryotic elongation factor 2 kinase requires intrinsic but not ongoing activity.Calyxin Y sensitizes cisplatin-sensitive and resistant hepatocellular carcinoma cells to cisplatin through apoptotic and autophagic cell death via SCF βTrCP-mediated eEF2K degradation.eEF-2 kinase is a critical regulator of Warburg effect through controlling PP2A-A synthesis.Natural autophagy regulators in cancer therapy: a reviewOverexpression of the recently identified oncogene REDD1 correlates with tumor progression and is an independent unfavorable prognostic factor for ovarian carcinoma
P2860
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P2860
Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Integrated regulation of autop ...... d velcade against tumor cells.
@ast
Integrated regulation of autop ...... d velcade against tumor cells.
@en
type
label
Integrated regulation of autop ...... d velcade against tumor cells.
@ast
Integrated regulation of autop ...... d velcade against tumor cells.
@en
prefLabel
Integrated regulation of autop ...... d velcade against tumor cells.
@ast
Integrated regulation of autop ...... d velcade against tumor cells.
@en
P2093
P2860
P356
P1433
P1476
Integrated regulation of autop ...... d velcade against tumor cells.
@en
P2093
Harold Harvey
Jin-Ming Yang
Kathryn J Huber-Keener
Leonard S Jefferson
Scot R Kimball
Xingcong Ren
P2860
P304
P356
10.4161/AUTO.22801
P577
2012-11-26T00:00:00Z