The recessive phenotype displayed by a dominant negative microphthalmia-associated transcription factor mutant is a result of impaired nucleation potential
about
Mitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.The microphthalmia transcription factor regulates expression of the tartrate-resistant acid phosphatase gene during terminal differentiation of osteoclastsA new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factorInteraction and cooperation of mi transcription factor (MITF) and myc-associated zinc-finger protein-related factor (MAZR) for transcription of mouse mast cell protease 6 geneIndependent influence of strain difference and mi transcription factor on the expression of mouse mast cell chymasesGenetic and phenotypic analysis of Tcm, a mutation affecting early eye developmentBiallelic Mutations in MITF Cause Coloboma, Osteopetrosis, Microphthalmia, Macrocephaly, Albinism, and DeafnessClinical and genetic investigation of families with type II Waardenburg syndrome.The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Commitment and differentiation of stem cells to the osteoclast lineage.A novel isoform of microphthalmia-associated transcription factor inhibits IL-8 gene expression in human cervical stromal cellsMITF and cell proliferation: the role of alternative splice forms.Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation.Genomic, transcriptional and mutational analysis of the mouse microphthalmia locusGenetic and phenotypic heterogeneity in Chinese patients with Waardenburg syndrome type II.Microphthalmia-associated transcription factor interactions with 14-3-3 modulate differentiation of committed myeloid precursorsNumber of mast cells in the peritoneal cavity of mice: influence of microphthalmia transcription factor through transcription of newly found mast cell adhesion molecule, spermatogenic immunoglobulin superfamily.Involvement of transcription factor encoded by the mouse mi locus (MITF) in apoptosis of cultured mast cells induced by removal of interleukin-3The semidominant Mi(b) mutation identifies a role for the HLH domain in DNA binding in addition to its role in protein dimerizationMolecular genetics and cellular features of TFE3 and TFEB fusion kidney cancersMITF links differentiation with cell cycle arrest in melanocytes by transcriptional activation of INK4AEffect of anatomical distribution of mast cells on their defense function against bacterial infections: demonstration using partially mast cell-deficient tg/tg mice.A general method to design dominant negatives to B-HLHZip proteins that abolish DNA binding.MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function.Interpretation of complex phenotypes: lessons from the Mitf gene.Combining integrated genomics and functional genomics to dissect the biology of a cancer-associated, aberrant transcription factor, the ASPSCR1-TFE3 fusion oncoprotein.A dominant negative mutant of microphthalmia transcription factor (MITF) lacking two transactivation domains suppresses transcription mediated by wild type MITF and a hyperactive MITF derivative.Specific Pax-6/microphthalmia transcription factor interactions involve their DNA-binding domains and inhibit transcriptional properties of both proteins.Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species.A novel CLTC-TFE3 gene fusion in pediatric renal adenocarcinoma with t(X;17)(p11.2;q23).Tietz syndrome: unique phenotype specific to mutations of MITF nuclear localization signal.Identification of promoter regions involved in cell- and developmental stage-specific osteopontin expression in bone, kidney, placenta, and mammary gland: an analysis of transgenic mice.Microphthalmia (mi) mice display an aberrant bone trace element composition.Wnt signaling pathway involvement in genotypic and phenotypic variations in Waardenburg syndrome type 2 with MITF mutations.
P2860
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P2860
The recessive phenotype displayed by a dominant negative microphthalmia-associated transcription factor mutant is a result of impaired nucleation potential
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The recessive phenotype displa ...... impaired nucleation potential
@ast
The recessive phenotype displa ...... impaired nucleation potential
@en
type
label
The recessive phenotype displa ...... impaired nucleation potential
@ast
The recessive phenotype displa ...... impaired nucleation potential
@en
prefLabel
The recessive phenotype displa ...... impaired nucleation potential
@ast
The recessive phenotype displa ...... impaired nucleation potential
@en
P2093
P2860
P356
P1476
The recessive phenotype displa ...... impaired nucleation potential
@en
P2093
Arnheiter H
Kitamura Y
Munakata H
Takebayashi K
Tsukamoto I
P2860
P304
P356
10.1128/MCB.16.3.1203
P407
P577
1996-03-01T00:00:00Z