Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
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The role of proopiomelanocortin (POMC) neurones in feeding behaviourThe melanocortin system and energy balanceDesign, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptorRecent advances in understanding leptin signaling and leptin resistance60 YEARS OF POMC: Regulation of feeding and energy homeostasis by α-MSHObesity genetics in mouse and human: back and forth, and back againGrowth Hormone Secretagogue Receptor Dimers: A New Pharmacological Target(1,2,3)Circadian adaptations to meal timing: neuroendocrine mechanismsTargeting central melanocortin receptors: a promising novel approach for treating alcohol abuse disordersMelanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward.Design, Synthesis, Structural and Functional Characterization of Novel Melanocortin Agonists Based on the Cyclotide Kalata B1Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5Activation of central melanocortin receptors by MT-II increases cavernosal pressure in rabbits by the neuronal release of NOAntibodies raised against different extracellular loops of the melanocortin-3 receptor affect energy balance and autonomic function in ratsThe melanocortin-3 receptor is required for entrainment to meal intakeIdentification of neuropeptide receptors expressed by melanin-concentrating hormone neurons.Melanocortin-3 receptors expressed in Nkx2.1(+ve) neurons are sufficient for controlling appetitive responses to hypocaloric conditioningMelanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells.Central nervous system melanocortin-3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle.Melanocortin-3 receptors and metabolic homeostasis.Sensory neuron-specific receptor activation elicits central and peripheral nociceptive effects in rats.Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor.Research resource: Gene profiling of G protein-coupled receptors in the arcuate nucleus of the female.Evidence of autocrine modulation of macrophage nitric oxide synthase by alpha-melanocyte-stimulating hormone.Prolylcarboxypeptidase (PRCP) as a new target for obesity treatmentDrug treatment of obesity: from past failures to future successes?Effects of melanocortin receptor activation and blockade on ethanol intake: a possible role for the melanocortin-4 receptor.Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).Neural regulation of innate immunity: a coordinated nonspecific host response to pathogens.An in Vitro and in Vivo Investigation of Bivalent Ligands That Display Preferential Binding and Functional Activity for Different Melanocortin Receptor Homodimers.Characterization of the hyperphagic response to dietary fat in the MC4R knockout mouse.Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position.Obesity therapy: altering the energy intake-and-expenditure balance sheet.Physiological roles of the melanocortin MC₃ receptor.Evaluation of hypothalamic murine and human melanocortin 3 receptor transcript structure.The natriuretic mechanism of Gamma-Melanocyte-Stimulating Hormone.Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs).Melanocortin control of energy balance: evidence from rodent models.An Obesity Risk SNP (rs17782313) near the MC4R Gene Is Associated with Cerebrocortical Insulin Resistance in Humans.Homeostastic and non-homeostatic functions of melanocortin-3 receptors in the control of energy balance and metabolism.
P2860
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P2860
Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Identification of a receptor f ...... hypothalamus and limbic system
@ast
Identification of a receptor f ...... hypothalamus and limbic system
@en
type
label
Identification of a receptor f ...... hypothalamus and limbic system
@ast
Identification of a receptor f ...... hypothalamus and limbic system
@en
prefLabel
Identification of a receptor f ...... hypothalamus and limbic system
@ast
Identification of a receptor f ...... hypothalamus and limbic system
@en
P2093
P2860
P356
P1476
Identification of a receptor f ...... hypothalamus and limbic system
@en
P2093
Entwistle ML
Mortrud MT
Mountjoy KG
Robbins LS
Roselli-Rehfuss L
Simerly RB
P2860
P304
P356
10.1073/PNAS.90.19.8856
P407
P577
1993-10-01T00:00:00Z