The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin
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Overview of AHR functional domains and the classical AHR signaling pathway: induction of drug-metabolizing enzymes2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhRSuperinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximideInfluence of light on aryl hydrocarbon receptor signaling and consequences in drug metabolism, physiology and diseaseSuperinduction of metallothionein I by inhibition of protein synthesis: role of a labile repressor in MTF-1 mediated gene transcriptionRegulation of transactivation function of the aryl hydrocarbon receptor by the Epstein-Barr virus-encoded EBNA-3 proteinIdentification of a novel mechanism of regulation of Ah (dioxin) receptor functionThe aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidizationUnderstanding the human health effects of chemical mixtures.Environmental Ligands of the Aryl Hydrocarbon Receptor and Their Effects in Models of Adult Liver Progenitor CellsThe role of the aryl hydrocarbon receptor in normal and malignant B cell developmentThe evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesisThe RelA NF-kappaB subunit and the aryl hydrocarbon receptor (AhR) cooperate to transactivate the c-myc promoter in mammary cellsDifferential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifsNedd9/Hef1/Cas-L mediates the effects of environmental pollutants on cell migration and plasticityA direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycleA novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxinAryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear exportIdentification and functional characterization of two highly divergent aryl hydrocarbon receptors (AHR1 and AHR2) in the teleost Fundulus heteroclitus. Evidence for a novel subfamily of ligand-binding basic helix loop helix-Per-ARNT-Sim (bHLH-PAS) fAh Receptor Pathway Intricacies; Signaling Through Diverse Protein Partners and DNA-MotifsThe anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptorRole of the coiled-coil coactivator (CoCoA) in aryl hydrocarbon receptor-mediated transcriptionConstitutive regulation of CYP1B1 by the aryl hydrocarbon receptor (AhR) in pre-malignant and malignant mammary tissueExpression of the aryl hydrocarbon receptor/transcription factor (AhR) and AhR-regulated CYP1 gene transcripts in a rat model of mammary tumorigenesisMolecular basis of dioxin actions: evidence supporting chemoprotection.Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention.The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.The aryl hydrocarbon receptor mediates raloxifene-induced apoptosis in estrogen receptor-negative hepatoma and breast cancer cells.Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein.Malignant transformation of mammary epithelial cells by ectopic overexpression of the aryl hydrocarbon receptorRecruitment of dioxin receptor to active transcription sites.The Aryl Hydrocarbon Receptor: A Target for Breast Cancer Therapy.Proteasome inhibition induces nuclear translocation and transcriptional activation of the dioxin receptor in mouse embryo primary fibroblasts in the absence of xenobioticsA constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors.The aryl hydrocarbon receptor functions as a tumor suppressor of liver carcinogenesis.The activated aryl hydrocarbon receptor synergizes mitogen-induced murine liver hyperplasiaThe aryl hydrocarbon receptor mediates leflunomide-induced growth inhibition of melanoma cells.Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A.The 2001 Veylien Henderson Award of the Society of Toxicology of Canada. Positive and negative transcriptional regulation of cytochromes P450 by polycyclic aromatic hydrocarbons.Stability of the aryl hydrocarbon receptor and its regulated genes in the low activity variant of Hepa-1 cell line
P2860
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P2860
The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The aromatic hydrocarbon recep ...... state independently of dioxin
@ast
The aromatic hydrocarbon recep ...... state independently of dioxin
@en
type
label
The aromatic hydrocarbon recep ...... state independently of dioxin
@ast
The aromatic hydrocarbon recep ...... state independently of dioxin
@en
prefLabel
The aromatic hydrocarbon recep ...... state independently of dioxin
@ast
The aromatic hydrocarbon recep ...... state independently of dioxin
@en
P2860
P356
P1476
The aromatic hydrocarbon recep ...... state independently of dioxin
@en
P2093
P2860
P304
P356
10.1128/MCB.16.5.2144
P407
P577
1996-05-01T00:00:00Z