about
Conformational selection in protein binding and functionShedding light on protein folding, structural and functional dynamics by single molecule studiesSingle-molecule dynamics and mechanisms of metalloregulators and metallochaperonesEvolutionarily conserved linkage between enzyme fold, flexibility, and catalysisSingle-molecule FRET of protein structure and dynamics - a primer.Revealing time bunching effect in single-molecule enzyme conformational dynamics.Enzymatic activation of nitro-aryl fluorogens in live bacterial cells for enzymatic turnover-activated localization microscopy†A practical guide to single-molecule FRETNew in silico and conventional in vitro approaches to advance HIV drug discovery and design.Redox cycling and kinetic analysis of single molecules of solution-phase nitrite reductaseContrasting the individual reactive pathways in protein unfolding and disulfide bond reduction observed within a single protein.Selective biomolecular nanoarrays for parallel single-molecule investigations.Fluorescence Intensity and Lifetime Cell Imaging with Luminescent Gold Nanoclusters."Eppur si muove" (Yet it moves).Single-molecule measurements of the opening and closing of the DNA gate by eukaryotic topoisomerase IIKinetic schemes for post-synchronized single molecule dynamics.Single-molecule fluorescence spectroscopy in (bio)catalysisSingle-molecule observation of DNA charge transfer.Single-molecule biophysics: at the interface of biology, physics and chemistryOptical-fiber bundles.Fluorescent avidin-bound silver particle: a strategy for single target molecule detection on a cell membrane.Time-dependent FRET with single enzymes: domain motions and catalysis in H(+)-ATP synthases.Artificial enzymes based on supramolecular scaffolds.Spatiotemporal catalytic dynamics within single nanocatalysts revealed by single-molecule microscopy.Zr-based metal-organic frameworks: design, synthesis, structure, and applications.Direct observation to chemokine receptor 5 on T-lymphocyte cell surface using fluorescent metal nanoprobes.Discrimination between conformational selection and induced fit protein-ligand binding using Integrated Global Fit analysis.Probing single biomolecules in solution using the anti-Brownian electrokinetic (ABEL) trap.Microfluidic mixer designed for performing single-molecule kinetics with confocal detection on timescales from milliseconds to minutes.Universal properties of mechanisms from two-state trajectories.The Orientations of Large Aspect-Ratio Coiled-Coil Proteins Attached to Gold Nanostructures.Handling and Sensing of Single Enzyme Molecules: From Fluorescence Detection towards Nanoscale Electrical Measurements.Selected-fit versus induced-fit protein binding: kinetic differences and mutational analysis.Conformational selection and induced changes along the catalytic cycle of Escherichia coli dihydrofolate reductase.Application of quantum mechanics/molecular mechanics methods in the study of enzymatic reaction mechanisms
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Single molecule studies of enzyme mechanisms.
@ast
Single molecule studies of enzyme mechanisms.
@en
type
label
Single molecule studies of enzyme mechanisms.
@ast
Single molecule studies of enzyme mechanisms.
@en
prefLabel
Single molecule studies of enzyme mechanisms.
@ast
Single molecule studies of enzyme mechanisms.
@en
P356
P1433
P1476
Single molecule studies of enzyme mechanisms.
@en
P2093
Gordon G Hammes
R Derike Smiley
P304
P356
10.1021/CR0502955
P577
2006-08-01T00:00:00Z