General Base-General Acid Catalysis in Human Histone Deacetylase 8.
about
Purification of metal-dependent lysine deacetylases with consistently high activity.Metal-dependent Deacetylases: Cancer and Epigenetic RegulatorsStructural aspects of HDAC8 mechanism and dysfunction in Cornelia de Lange syndrome spectrum disorders.Histone deacetylase 6 structure and molecular basis of catalysis and inhibition.Structural and Functional Influence of the Glycine-Rich Loop G302GGGY on the Catalytic Tyrosine of Histone Deacetylase 8.Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.Structure-activity relationships of hydroxamate-based histone deacetylase-8 inhibitors: reality behind anticancer drug discovery.HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides.Chelatable trace zinc causes low, irreproducible KDAC8 activity.Binding of the Microbial Cyclic Tetrapeptide Trapoxin A to the Class I Histone Deacetylase HDAC8.
P2860
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P2860
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@ast
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@en
type
label
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@ast
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@en
prefLabel
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@ast
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@en
P2093
P2860
P1433
P1476
General Base-General Acid Catalysis in Human Histone Deacetylase 8.
@en
P2093
Carol A Fierke
Christine M Bowman
Christophe Decroos
David W Christianson
Laura E Gullett
Matthew S Lee
Sister M Lucy Gantt
P2860
P304
P356
10.1021/ACS.BIOCHEM.5B01327
P407
P577
2016-01-25T00:00:00Z