Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy.
about
Protein kinase cascades in the regulation of cardiac hypertrophyTransient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathwaysPKC translocation and ERK1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysemaHow exercise may amend metabolic disturbances in diabetic cardiomyopathyProtein kinase C mechanisms that contribute to cardiac remodellingPKCepsilon activation induces dichotomous cardiac phenotypes and modulates PKCepsilon-RACK interactions and RACK expressionCharacterization of protein kinase C beta isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation, and retinal neovascularization.Involvement of protein kinase C beta 2 in c-myc induction by high glucose in pancreatic beta-cellsPKC alpha regulates the hypertrophic growth of cardiomyocytes through extracellular signal-regulated kinase1/2 (ERK1/2)Akt-mediated cardiomyocyte survival pathways are compromised by G alpha q-induced phosphoinositide 4,5-bisphosphate depletionN-acetylcysteine attenuates PKCbeta2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic ratsC2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound stateProtein quality control disruption by PKCβII in heart failure; rescue by the selective PKCβII inhibitor, βIIV5-3CapZ dynamics are altered by endothelin-1 and phenylephrine via PIP2- and PKC-dependent mechanisms.Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.Pleiotropy, homeostasis, and functional networks based on assays of cardiovascular traits in genetically randomized populationsPKCβII modulation of myocyte contractile performance.Regulation of the ligand binding activity of the human very low density lipoprotein receptor by protein kinase C-dependent phosphorylation.Brief rapid pacing depresses contractile function via Ca(2+)/PKC-dependent signaling in cat ventricular myocytes.Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation.HIV replication enhances production of free fatty acids, low density lipoproteins and many key proteins involved in lipid metabolism: a proteomics studyMammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats.Molecular Signals Elicited by GPCR Agonists in Hypertension, Cardiovascular Remodeling: Are MMPs and ADAMs Elusive Therapeutic Targets?Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouseDeficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunctionMeeting Koch's postulates for calcium signaling in cardiac hypertrophy.A positive feedback loop contributes to the deleterious effects of angiotensin.Therapeutic potential of endothelin receptor antagonists in diabetes.Protein kinase C activation and its pharmacological inhibition in vascular disease.Diabetic cardiomyopathy: recent evidence from mouse models of type 1 and type 2 diabetes.Highly Specific Modulators of Protein Kinase C Localization: Applications to Heart FailureCardiac hypertrophy and failure: lessons learned from genetically engineered mice.Coronary microvascular dysfunction in diabetes mellitus: A reviewProtein kinase C and the development of diabetic vascular complications.Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.βIIPKC and εPKC isozymes as potential pharmacological targets in cardiac hypertrophy and heart failurePKCβII inhibition attenuates myocardial infarction induced heart failure and is associated with a reduction of fibrosis and pro-inflammatory responsesPreventing progression of cardiac hypertrophy and development of heart failure by paricalcitol therapy in rats.Endothelins in chronic diabetic complications.Gαq protein carboxyl terminus imitation polypeptide GCIP-27 improves cardiac function in chronic heart failure rats.
P2860
Q24518494-BCD6F2AA-9239-4E15-9435-7AAC23448B40Q24649132-BE7AD390-7718-494A-BAE8-1372C3D841B2Q24810204-DC4CBDE9-2FE7-41E9-86E0-1B6F067E2A1AQ26863272-9341A7C4-6792-4764-A8B9-BA1C19F622B4Q28075729-52FE21FB-F114-4216-8159-10E7629E9763Q28200094-159B8BC9-B02E-4F26-96A2-D9D5743CBDDDQ28504628-E8DC1E0E-80D9-43A7-AA42-77D6A2B4773CQ28566691-BE29AB8A-3B2D-4A37-9F73-0980AF6E91F8Q28567395-F2F70B92-38A8-44A3-B5D4-69B6BA8A18EBQ28571127-EB7546A6-4B3A-426E-84CB-18D845FFE72BQ28573358-90340946-66A7-4F67-A36F-F2D792DE2463Q28613889-BB516035-AFA7-45D5-91B9-202E630549E9Q28730834-5AD9CE06-AFC5-43AE-BAEC-F52D1B7DDD6DQ30436192-421F0BB9-C70C-4425-BA43-6F99D2CA19A9Q30479148-77DF49C0-ED0D-4BD2-8F3F-DFE9FD767682Q30501139-02BC26B3-F5C7-4D7F-81C8-4C9887CA92C3Q30524184-46501DB7-8CE8-441B-A642-4EA214FED928Q31442067-13CBE698-8081-49DF-B5F4-CBD172BF5FA7Q31722171-3CDC9AC2-5F30-4213-98C4-A9327ABBF5D9Q33214227-CC0B0AB2-26C9-47EF-B27E-43F18E589989Q33361587-42A333D6-DDF7-42C3-8705-42BE2346389AQ33576908-0D7314E6-87BA-4A0B-864D-02185C33C4B1Q33807091-639D0803-27CF-4CAA-9798-8531CF841057Q33858191-3B4F9504-1FC7-4D9A-95F4-16A396F51579Q33899819-8B17A3CB-D48F-4313-8A3F-FA258EEA609FQ33919182-EF0CE220-4A81-431A-82FC-51338D168EFCQ34078545-969442B1-F08E-4EE3-87F4-9C56231EC561Q34090982-08656FC7-3E39-43E5-AEBD-847A64AA0114Q34097328-97FF604E-C3B1-410E-80A5-52C9F6110D77Q34372508-D31907A3-4C0C-4B64-9CC4-FAFF30743501Q34386778-0486B8D8-B577-43FE-B06A-7A16ACC65ABAQ34418993-78EDA889-5FCB-41BD-926A-6FD06F03DA97Q34427072-A8B20975-F749-443D-8286-6D1F9EBE6888Q34570516-CADFD20F-A1DB-4541-8055-3B75FED60AFFQ34766977-449BBBBF-1B2F-4729-B9A1-002AC11DDEABQ35103455-9BCC2073-16D4-445A-9274-8625959B538DQ35106609-95EE4FA4-1C38-432D-BFE0-359F03CE557FQ35167070-A57727C0-BF35-419A-949A-F7E9B3D098DCQ35168430-781E46F0-0D88-4F69-8E69-CF084F3858E9Q35231792-B582ECC8-4A58-44B5-94F1-FC4043499422
P2860
Targeted overexpression of protein kinase C beta2 isoform in myocardium causes cardiomyopathy.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@ast
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@en
type
label
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@ast
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@en
prefLabel
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@ast
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@en
P2093
P2860
P356
P1476
Targeted overexpression of pro ...... cardium causes cardiomyopathy.
@en
P2093
F J Schoen
H Wakasaki
M R Jirousek
P2860
P304
P356
10.1073/PNAS.94.17.9320
P407
P577
1997-08-01T00:00:00Z