Cell transformation mediated by homodimeric E2A-HLF transcription factors. - Wikidata - wikimedia - TriplyDB

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

http://www.wikidata.org/entity/Q36565887

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The AD1 and AD2 transactivation domains of E2A are essential for the antiapoptotic activity of the chimeric oncoprotein E2A-HLF Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic mice Two distinct interleukin-3-mediated signal pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, regulate the survival of murine pro-B lymphocytes.An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogene Role for homodimerization in growth deregulation by E2a fusion proteins.E2A-HLF usurps control of evolutionarily conserved survival pathways.Transcription factor RF2a alters expression of the rice tungro bacilliform virus promoter in transgenic tobacco plants.Attractive interhelical electrostatic interactions in the proline- and acidic-rich region (PAR) leucine zipper subfamily preclude heterodimerization with other basic leucine zipper subfamilies.Novel member of the PAR domain bZIP gene family isolated from Pacific oyster, Crassostrea gigas.Oncogenic fusion E2A-HLF sensitizes t(17;19)-positive acute lymphoblastic leukemia to TRAIL-mediated apoptosis by upregulating the expression of death receptors.The E2A-HLF oncoprotein activates Groucho-related genes and suppresses Runx1.Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity.Identification of Zfp521/ZNF521 as a cooperative gene for E2A-HLF to develop acute B-lineage leukemia.Hypercalcemia in childhood acute lymphoblastic leukemia: frequent implication of parathyroid hormone-related peptide and E2A-HLF from translocation 17;19.

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P2860

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

http://www.wikidata.org/entity/Q36565887

description

1997 nî lūn-bûn

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1997年の論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年論文

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1997年论文

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1997年论文

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1997年论文

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name

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

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Cell transformation mediated by homodimeric E2A-HLF transcription factors.

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type

label

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

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Cell transformation mediated by homodimeric E2A-HLF transcription factors.

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prefLabel

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

@ast

Cell transformation mediated by homodimeric E2A-HLF transcription factors.

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Molecular and Cellular Biology

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Cell transformation mediated by homodimeric E2A-HLF transcription factors.

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P2860

Fusion of the leucine zipper gene HLF to the E2A gene in human acute B-lineage leukemia

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter

Chromosomal localization and cDNA cloning of the human DBP and TEF genes

The proto-oncogene HLF and the related basic leucine zipper protein TEF display highly similar DNA-binding and transcriptional regulatory properties

EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

Transcriptional repression by a novel member of the bZIP family of transcription factors

DNA-binding and transcriptional regulatory properties of hepatic leukemia factor (HLF) and the t(17;19) acute lymphoblastic leukemia chimera E2A-HLF

DNA-binding specificity and trans-activating potential of the leukemia-associated E2A-hepatic leukemia factor fusion protein

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1417-1424

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10.1128/MCB.17.3.1417

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17

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14178657

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9032268

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231866

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