The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. - Wikidata - wikimedia - TriplyDB

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

http://www.wikidata.org/entity/Q36567141

about

Harnessing Mechanistic Knowledge on Beneficial Versus Deleterious IFN-I Effects to Design Innovative Immunotherapies Targeting Cytokine Activity to Specific Cell Types Current trends in oxysterol research Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus Infection homeostasis: implications for therapeutic and immune programming of metabolism in controlling infection Effects of Interferons and Viruses on Metabolism Surfactant Lipids at the Host-Environment Interface. Metabolic Sensors, Suppressors, and Effectors of Inflammatory Lung Disease Role for phospholipid acyl chains and cholesterol in pulmonary infections and inflammation An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway 25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model Liver X Receptors Link Lipid Metabolism and Inflammation.Characterization of Glycoprotein-Mediated Entry of Severe Fever with Thrombocytopenia Syndrome Virus Modeling genome-wide dynamic regulatory network in mouse lungs with influenza infection using high-dimensional ordinary differential equations.Tracking the subcellular fate of 20(s)-hydroxycholesterol with click chemistry reveals a transport pathway to the Golgi.Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.Viral MicroRNAs Repress the Cholesterol Pathway, and 25-Hydroxycholesterol Inhibits Infection.Innate immunity to influenza virus infection.25-Hydroxycholesterol acts as an amplifier of inflammatory signaling.Microbes and Alzheimer's Disease.Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibition Absence of Nceh1 augments 25-hydroxycholesterol-induced ER stress and apoptosis in macrophages Epigenetic regulation of cholesterol homeostasis.Interferon-stimulated genes: a complex web of host defenses.Interferon-inducible cholesterol-25-hydroxylase inhibits hepatitis C virus replication via distinct mechanisms.Inhibition of pathogenic non-enveloped viruses by 25-hydroxycholesterol and 27-hydroxycholesterol.High-throughput screening normalized to biological response: application to antiviral drug discovery.The major cellular sterol regulatory pathway is required for Andes virus infection The mutual interplay of lipid metabolism and the cells of the immune system in relation to atherosclerosis Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature Identification of Cholesterol 25-Hydroxylase as a Novel Host Restriction Factor and a Part of the Primary Innate Immune Responses against Hepatitis C Virus Infection RORα and 25-Hydroxycholesterol Crosstalk Regulates Lipid Droplet Homeostasis in Macrophages Impact of selenium supplementation on fish antiviral responses: a whole transcriptomic analysis in rainbow trout (Oncorhynchus mykiss) fed supranutritional levels of Sel-Plex®.Cholesterolomics: An update Time resolved and label free monitoring of extracellular metabolites by surface enhanced Raman spectroscopy The greasy response to virus infections.Subverting sterols: rerouting an oxysterol-signaling pathway to promote tumor growth How are STAT1 and cholesterol metabolism associated in antiviral responses?Deciphering the modulation of gene expression by type I and II interferons combining 4sU-tagging, translational arrest and in silico promoter analysis.HIV-1 Trans Infection of CD4(+) T Cells by Professional Antigen Presenting Cells 25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.

P2860

Q21131160-5633513B-0386-4E28-8160-0BF843585078 Q26749224-63294CB1-2B3A-4FD6-8735-3204750175A6 Q26800190-9CF272DC-AFBA-4B2D-9188-EE6E74A5E7F7 Q27319958-2AF0EBA6-3934-4BD7-A74B-612043543D6C Q28083186-82DA7ECB-4E45-4158-A534-DB9C00B0F76B Q28353943-B2E266A7-7145-4049-B949-6F660A9F2936 Q28383936-C4F8E852-B973-40A7-A6F8-6FC47B3D8E07 Q28391857-0CD6CA72-BE00-4E24-9BA5-F8A9C6E44FB8 Q28550521-AFCA8299-423F-41C8-8296-4E23BEC26927 Q28950498-B2A7FD64-FCC8-46A5-B27C-43EEC56AF943 Q30252316-4F648C61-8F85-4A94-AE2B-310B2B2BAAEA Q33430785-2AE68A24-0D16-4675-89BE-80C30CF29004 Q33572880-922577AF-9530-4DC2-8A18-486DFD54CFFB Q33676201-74085AE6-3EC3-4F9E-8EA9-E8F440BC3BCD Q33743822-AE3AF924-835D-4F93-8E1B-16FA95432F2B Q33911258-822F4FFD-DCB8-4FF5-8E28-EE285220CC4A Q33923354-C744A3CA-61F0-475D-9697-8E6BA4F2F8DF Q33972004-00956337-FFB3-49E8-8CA8-CE775C328409 Q34046427-17966321-4D04-4DA3-9DC6-3F03357EEAA6 Q34170578-700B1886-4606-4DB2-94AF-39BB6B0D5950 Q34238679-0A780594-5341-4859-B828-8AAC421D5E5A Q34238886-B63B3DEC-379E-4F13-BB71-A7838D0D613E Q34405609-BEE159D4-E7A2-4315-9BA7-F3187A56A3D1 Q34616709-158EBC3C-8117-4A05-91C7-917B11035403 Q34698858-1F8DFA96-6226-4D69-BAA4-7E506D117218 Q34824028-2985C1A8-745E-4A43-976E-3AB12A71AA50 Q35091225-8A5A581B-57D4-4181-9760-7FF99FFD082B Q35104236-90FB9C47-44EC-438B-B69F-AA5D4792AE7A Q35127516-8EA380EB-974D-46DD-BBD9-1CE917DF4AF0 Q35745376-51BEEF9A-A41B-494A-B8D2-90F658E268EA Q35905052-80C79566-B693-414F-8378-26571D61B519 Q35924600-993E37A9-CA8D-4F9D-A442-5C6B01DB452F Q36249577-ED28613A-4874-454C-9E17-13728CCB02B4 Q36349681-759173EF-537F-4546-8A38-F1A657A13AE0 Q36846100-A1CC6012-E6E0-4657-82B8-C899FAAB5300 Q37125772-FE8E0951-B38E-461A-ACC4-F5049E06B7BE Q37168120-C48A914E-DB09-4876-AD30-5754161B6C0B Q37197803-E86FF95D-D5E7-4551-987F-25E8C96A00A8 Q37287774-56759E39-C56C-466A-BAA7-6D4D4A5473B9 Q37388798-F1E66B2D-319E-41CE-A88C-91CA17437081

P2860

The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response.

http://www.wikidata.org/entity/Q36567141

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

The transcription factor STAT- ...... interferon antiviral response.

@ast

The transcription factor STAT- ...... interferon antiviral response.

@en

type

label

The transcription factor STAT- ...... interferon antiviral response.

@ast

The transcription factor STAT- ...... interferon antiviral response.

@en

prefLabel

The transcription factor STAT- ...... interferon antiviral response.

@ast

The transcription factor STAT- ...... interferon antiviral response.

@en

P1433

Q36567141-79D86FF7-4B62-4309-8B92-59F1921B0446

P1476

Q36567141-A01CBEC6-5A56-433B-A690-E5EE6AFD67A0

P2093

Q36567141-1DCD6B59-E141-48FE-B702-F9BBD1552C36

Q36567141-288DA9F4-84DF-42D5-84BE-9DC673A57A2A

Q36567141-2CF6918D-3B60-435A-8BF9-7E6744991887

Q36567141-39BB0BE8-00C4-4B12-885A-08E5BED9487A

Q36567141-5218BCD9-C156-4086-A365-98D3BA0692E7

Q36567141-552B0951-DFA9-486A-BBE6-75139C4306D3

Q36567141-65D46BF8-4261-421C-81AE-474A9CE7CA85

Q36567141-7437C1DB-C559-498E-B1E2-49A2E0D612F5

Q36567141-8709B50B-E14F-4BE1-8252-898B04EFD8EC

Q36567141-94FBA3B1-C314-4AF3-B808-D941A5F757D9

P2860

Q36567141-00317FFD-CE4B-48FA-99B7-CA58986E4392

Q36567141-01313A04-2E32-4E37-897A-A9E3F4605A69

Q36567141-058139B0-EF96-46AB-926A-DC80D19C7E6F

Q36567141-066E3DB3-13C1-47D7-AB08-C8BD5A1E9443

Q36567141-0761677C-74E3-4280-998A-E18DCFB8D0F9

Q36567141-1E01A04A-C12C-4D34-8103-9A708F6BCCB0

Q36567141-222B6BC0-CF4E-438A-B8D4-46164DD7AFA7

Q36567141-279F73DD-8441-432A-B682-AE98E5AE0120

Q36567141-2ADE38B2-B5B0-466B-8D2D-B337AF313747

Q36567141-34D24FC4-AD31-4A3A-A891-DD86424077F2

P304

Q36567141-79D25022-31C2-4241-9228-98093EAA8EAA

P31

Q36567141-EE319C3E-A680-4E16-8D8A-1C2322CEE4D6

P356

Q36567141-0186D20B-520E-46B5-8ED6-68AA93905DBD

P407

Q36567141-FF51CA70-0E3F-4BC5-9A48-452B650E80F5

P433

Q36567141-749E8DF9-5384-4274-90E4-44D60B3CC81C

P478

Q36567141-C24B9B54-8782-4DFE-AA6A-F00B6C9FBB4C

P50

Q36567141-0381939E-B15E-4CF1-B0D8-BFCAB1AF432B

Q36567141-8155848A-8A91-4EA1-B938-7F4D9D6E11EB

Q36567141-9584ECF9-87DF-4DA7-A058-EB292DA1DF36

Q36567141-A55EA6C1-6166-4F10-80E2-18179494CBD8

Q36567141-D763038F-2C96-4483-BEC0-C28A85018412

Q36567141-E5970D76-A906-4650-81A7-833F387EFC90

Q36567141-FDB2C8B4-825B-4A00-B93D-74CB235C5C85

P577

Q36567141-6A929A01-1D01-4CF8-BB59-D186A274DBE6

P5875

Q36567141-6167BE7F-8D57-4491-A9E1-251682880BF3

P698

Q36567141-19591809-9060-49AB-A11F-890BFEF2C0CA

P921

Q36567141-3F732AAB-D92F-4004-9985-1DB8C80E1DED

P932

Q36567141-D722E0C9-9719-4B4E-B8D7-2F18A989AED9

P356

J.IMMUNI.2012.11.004

P1433

P1476

The transcription factor STAT- ...... interferon antiviral response.

@en

P2093

Anna Meljon

http://www.w3.org/2001/XMLSchema#string

Christopher K Glass

http://www.w3.org/2001/XMLSchema#string

Douglas F Covey

http://www.w3.org/2001/XMLSchema#string

Guanghou Shui

http://www.w3.org/2001/XMLSchema#string

Jürgen Haas

http://www.w3.org/2001/XMLSchema#string

Kathiresan Krishnan

http://www.w3.org/2001/XMLSchema#string

Kevin A Robertson

http://www.w3.org/2001/XMLSchema#string

Marie Craigon

http://www.w3.org/2001/XMLSchema#string

Markus R Wenk

http://www.w3.org/2001/XMLSchema#string

Mathieu Blanc

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins

Oxysterols direct immune cell migration via EBI2

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig

Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins

Psoromic acid is a selective and covalent Rab-prenylation inhibitor targeting autoinhibited RabGGTase

Antiviral activity of lovastatin against respiratory syncytial virus in vivo and in vitro

Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

Early dengue virus protein synthesis induces extensive rearrangement of the endoplasmic reticulum independent of the UPR and SREBP-2 pathway

Oxysterols direct B-cell migration through EBI2

P304

106-118

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.IMMUNI.2012.11.004

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

38

http://www.w3.org/2001/XMLSchema#string

P50

Steven Watterson

Thorsten Forster

William J Griffiths

P577

2012-12-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

234010509

http://www.w3.org/2001/XMLSchema#string

P698

23273843

http://www.w3.org/2001/XMLSchema#string

P921

P932

3556782

http://www.w3.org/2001/XMLSchema#string