The mighty mouse: genetically engineered mouse models in cancer drug development.
about
Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimagingNext generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor targetDNA damage-mediated induction of a chemoresistant nicheSuppression of Rev3, the catalytic subunit of Pol{zeta}, sensitizes drug-resistant lung tumors to chemotherapyHigh sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugsImaging in the era of molecular oncology.Murine models to evaluate novel and conventional therapeutic strategies for cancerManipulation of DNA Repair Proficiency in Mouse Models of Colorectal CancerPatient-derived xenograft models of colorectal cancer in pre-clinical research: a systematic reviewINFRAFRONTIER: a European resource for studying the functional basis of human diseaseGEMMs as preclinical models for testing pancreatic cancer therapiesUse of rodents as models of human diseasesRegulation of Nrf2-Mediated Phase II Detoxification and Anti-oxidant GenesHooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic eraContemporary murine models in preclinical astrocytoma drug developmentA murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formationPreclinical mouse cancer models: a maze of opportunities and challenges.Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer AgentsMouse models of colorectal cancer as preclinical modelsNovel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafishHuman Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-ImagingImaging biomarker roadmap for cancer studiesImaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma.Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation modelImaging primary lung cancers in mice to study radiation biology.Therapeutically targeting cyclin D1 in primary tumors arising from loss of Ini1.Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endotheliumEfficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical DataHuman tumor xenograft models for preclinical assessment of anticancer drug development.Cytosolic Hsp90α and its mitochondrial isoform Trap1 are differentially required in a breast cancer model.The AML salad bowl.Modeling nasopharyngeal carcinoma in three dimensionsDocetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment.Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity.Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.Use of mouse models to study the role of tissue factor in tumor biologyUse of the ODD-luciferase transgene for the non-invasive imaging of spontaneous tumors in mice.Stability of preclinical models of aggressive renal cell carcinomas.
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The mighty mouse: genetically engineered mouse models in cancer drug development.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
The mighty mouse: genetically engineered mouse models in cancer drug development.
@ast
The mighty mouse: genetically engineered mouse models in cancer drug development.
@en
type
label
The mighty mouse: genetically engineered mouse models in cancer drug development.
@ast
The mighty mouse: genetically engineered mouse models in cancer drug development.
@en
prefLabel
The mighty mouse: genetically engineered mouse models in cancer drug development.
@ast
The mighty mouse: genetically engineered mouse models in cancer drug development.
@en
P356
P1476
The mighty mouse: genetically engineered mouse models in cancer drug development.
@en
P2093
Ronald A Depinho
P2860
P2888
P304
P356
10.1038/NRD2110
P577
2006-08-18T00:00:00Z
P6179
1008760692