Efficient repression of endogenous major histocompatibility complex class II expression through dominant negative CIITA mutants isolated by a functional selection strategy.
about
Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repairPML promotes MHC class II gene expression by stabilizing the class II transactivatorNew functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis studySendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosisCIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivationClass II transactivator: mastering the art of major histocompatibility complex expressionA functionally essential domain of RFX5 mediates activation of major histocompatibility complex class II promoters by promoting cooperative binding between RFX and NF-YThe RFX family interacts at the collagen (COL1A2) start site and represses transcriptionHepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2Expression of the three human major histocompatibility complex class II isotypes exhibits a differential dependence on the transcription factor RFXAPPromoter-specific functions of CIITA and the MHC class II enhanceosome in transcriptional activationThe amino-terminal extensions of the longer Sendai virus C proteins modulate pY701-Stat1 and bulk Stat1 levels independently of interferon signaling.CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complexDegradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform IIIActivation of the beta interferon promoter by unnatural Sendai virus infection requires RIG-I and is inhibited by viral C proteinsMaturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression.A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability.Recent patents on therapeutic applications of the transcription factor decoy approach.Antipsychotic treatment modulates glutamate transport and NMDA receptor expression.Self-association of class II transactivator correlates with its intracellular localization and transactivation.The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element.Evidence that Receptor Destruction by the Sendai Virus Hemagglutinin-Neuraminidase Protein Is Responsible for Homologous Interference.Downregulation of CIITA function by protein kinase a (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic linesInvolvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator.CIITA mediates interferon-gamma repression of collagen transcription through phosphorylation-dependent interactions with co-repressor molecules.Targeting of the Sendai virus C protein to the plasma membrane via a peptide-only membrane anchor.Development of potent class II transactivator gene delivery systems capable of inducing de novo MHC II expression in human cells, in vitro and ex vivo.Chromatin remodeling and extragenic transcription at the MHC class II locus control region.Combinations of dominant-negative class II transactivator, p300 or CDK9 proteins block the expression of MHC II genes.Enhanced growth of influenza A virus by coinfection with human parainfluenza virus type 2.Quantitative control of MHC class II expression by the transactivator CIITA.Primary human articular chondrocytes, dedifferentiated chondrocytes, and synoviocytes exhibit differential responsiveness to interleukin-4: correlation with the expression pattern of the common receptor gamma chain.Structural and functional characteristics of a dominant-negative isoform of porcine MHC class II transactivator.
P2860
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P2860
Efficient repression of endogenous major histocompatibility complex class II expression through dominant negative CIITA mutants isolated by a functional selection strategy.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Efficient repression of endoge ...... functional selection strategy.
@ast
Efficient repression of endoge ...... functional selection strategy.
@en
type
label
Efficient repression of endoge ...... functional selection strategy.
@ast
Efficient repression of endoge ...... functional selection strategy.
@en
prefLabel
Efficient repression of endoge ...... functional selection strategy.
@ast
Efficient repression of endoge ...... functional selection strategy.
@en
P2093
P2860
P356
P1476
Efficient repression of endoge ...... functional selection strategy.
@en
P2093
P2860
P304
P356
10.1128/MCB.17.8.4249
P407
P577
1997-08-01T00:00:00Z