Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities.
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P1343
The human non-muscle alpha-actinin protein encoded by the ACTN4 gene suppresses tumorigenicity of human neuroblastoma cellsAssociation of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activationalpha-Catenin-vinculin interaction functions to organize the apical junctional complex in epithelial cellsThe tumor-suppressor function of E-cadherinAlpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1Distinct activities of the alpha-catenin family, alpha-catulin and alpha-catenin, on beta-catenin-mediated signalingDifferential nuclear translocation and transactivation potential of beta-catenin and plakoglobinCharacterization of the gene encoding pinin/DRS/memA and evidence for its potential tumor suppressor functionIQGAP1-mediated stimulation of transcriptional co-activation by beta-catenin is modulated by calmodulinVinculin is associated with the E-cadherin adhesion complexA mutation in alpha-catenin disrupts adhesion in clone A cells without perturbing its actin and beta-catenin binding activityDLC1 interaction with α-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activityDistinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes.Transendothelial migration of melanoma cells involves N-cadherin-mediated adhesion and activation of the beta-catenin signaling pathwayThe evolutionary origin of epithelial cell-cell adhesion mechanismsE-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion.The cadherin-catenin adhesion system in signaling and cancer.Cadherin and catenin alterations in human cancer.Alpha-catenin: at the junction of intercellular adhesion and actin dynamicsUtility of multispectral imaging in automated quantitative scoring of immunohistochemistry.E-Cadherin-dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27(KIP1)Molecular components of the adherens junction.αE-catenin inhibits a Src-YAP1 oncogenic module that couples tyrosine kinases and the effector of Hippo signaling pathway.Alpha-E-catenin binds to dynamitin and regulates dynactin-mediated intracellular trafficDanio rerio αE-catenin is a monomeric F-actin binding protein with distinct properties from Mus musculus αE-catenin.Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3.Role of epithelial to mesenchymal transition proteins in gynecological cancers: pathological and therapeutic perspectives.Identification of the region of alpha-catenin that plays an essential role in cadherin-mediated cell adhesion.Signatures of mutation and selection in the cancer genome.Four human breast cancer cell lines with biallelic inactivating alpha-catenin gene mutations.Modulation of the tumor suppressor protein alpha-catenin by ischemic microenvironment.GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alphaT-catenin gene CTNNA3.alpha-Catenin overrides Src-dependent activation of beta-catenin oncogenic signaling.Evidence for a potential tumor suppressor role for the Na,K-ATPase beta1-subunit.Alpha(E)-Catenin induces SRF-dependent transcriptional activity through its C-terminal region and is partly RhoA/ROCK-dependent.Direct interaction of the C-terminal domain of alpha-catenin and F-actin is necessary for stabilized cell-cell adhesion.Induction of invasion in vivo of alpha-catenin-positive HCT-8 human colon-cancer cells.alpha-catenin inhibits beta-catenin signaling by preventing formation of a beta-catenin*T-cell factor*DNA complex.Novel insight into the function and regulation of alphaN-catenin by Snail2 during chick neural crest cell migration.
P2860
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P2860
Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Expression of wild-type alpha- ...... d tumor suppressor activities.
@ast
Expression of wild-type alpha- ...... d tumor suppressor activities.
@en
type
label
Expression of wild-type alpha- ...... d tumor suppressor activities.
@ast
Expression of wild-type alpha- ...... d tumor suppressor activities.
@en
prefLabel
Expression of wild-type alpha- ...... d tumor suppressor activities.
@ast
Expression of wild-type alpha- ...... d tumor suppressor activities.
@en
P2093
P2860
P356
P1476
Expression of wild-type alpha- ...... d tumor suppressor activities.
@en
P2093
A J Levine
D A Notterman
L C Bullions
P2860
P304
P356
10.1128/MCB.17.8.4501
P407
P4510
P577
1997-08-01T00:00:00Z