Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics.

Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics.

Item
http://www.wikidata.org/entity/Q36570454
Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor.Antiestrogens: structure-activity relationships and use in breast cancer treatmentDifferent classes of coactivators recognize distinct but overlapping binding sites on the estrogen receptor ligand binding domainAntifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug actionMutations of ESRRB encoding estrogen-related receptor beta cause autosomal-recessive nonsyndromic hearing impairment DFNB35.Serine protease PRSS23 is upregulated by estrogen receptor α and associated with proliferation of breast cancer cells.Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer.Mutation of Leu-536 in human estrogen receptor-alpha alters the coupling between ligand binding, transcription activation, and receptor conformation.Aspartate 351 of estrogen receptor alpha is not crucial for the antagonist activity of antiestrogens.Directed evolution of orthogonal ligand specificity in a single scaffold.Directed evolution of human estrogen receptor variants with significantly enhanced androgen specificity and affinity.Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3.
P2860

Probing the structure and function of the estrogen receptor ligand binding domain by analysis of mutants with altered transactivation characteristics.

Item
http://www.wikidata.org/entity/Q36570454
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Probing the structure and func ...... ansactivation characteristics.
@ast
Probing the structure and func ...... ansactivation characteristics.
@en
type
label
Probing the structure and func ...... ansactivation characteristics.
@ast
Probing the structure and func ...... ansactivation characteristics.
@en
prefLabel
Probing the structure and func ...... ansactivation characteristics.
@ast
Probing the structure and func ...... ansactivation characteristics.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932
P356
P1433
P1476
Probing the structure and func ...... ansactivation characteristics.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P5875
P698
P921
P932