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Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

http://www.wikidata.org/entity/Q36582802

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Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"The genetics of cancer risk The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making MSMB variation and prostate cancer risk: clues towards a possible fungal etiology GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database Genome-wide association study identifies new prostate cancer susceptibility loci A genome-wide search for loci interacting with known prostate cancer risk-associated genetic variants Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese Genetic variation in prostate-specific antigen-detected prostate cancer and the effect of control selection on genetic association studies A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.Genome-wide association study identifies a common variant associated with risk of endometrial cancer.Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.Discovery and fine-mapping of adiposity loci using high density imputation of genome-wide association studies in individuals of African ancestry: African Ancestry Anthropometry Genetics Consortium.Hypothesis driven single nucleotide polymorphism search (HyDn-SNP-S).Genome-wide association study identifies a genetic variant associated with risk for more aggressive prostate cancer.Reclassification of genetic-based risk predictions as GWAS data accumulate.Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status.Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer.Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.Comparison of two methods for estimating absolute risk of prostate cancer based on single nucleotide polymorphisms and family history.Genome-wide association studies in cancer--current and future directions Refining the prostate cancer genetic association within the JAZF1 gene on chromosome 7p15.2.Characterizing associations and SNP-environment interactions for GWAS-identified prostate cancer risk markers--results from BPC3.Evaluation of polygenic risk scores for predicting breast and prostate cancer risk.SNP-based pathway enrichment analysis for genome-wide association studies A compendium of genome-wide associations for cancer: critical synopsis and reappraisal.Characterizing genetic risk at known prostate cancer susceptibility loci in African Americans Prostate cancer risk alleles are associated with prostate cancer volume and prostate size.Multiple loci are associated with white blood cell phenotypes.Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4.A comprehensive analysis of common IGF1, IGFBP1 and IGFBP3 genetic variation with prospective IGF-I and IGFBP-3 blood levels and prostate cancer risk among Caucasians A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression.Genetic variation in RNASEL associated with prostate cancer risk and progression.Evaluation of breast cancer susceptibility loci in Chinese women.Molecular genetics of prostate cancer: new prospects for old challenges Prostate cancer susceptibility variants confer increased risk of disease progression.Genome-wide association studies of cancer.Pooled sample-based GWAS: a cost-effective alternative for identifying colorectal and prostate cancer risk variants in the Polish population.

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P2860

Genome-wide association and replication studies identify four variants associated with prostate cancer susceptibility

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Arnaldur Gylfason

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Asgeir Sigurdsson

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Berta Saez

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Bjarni A Agnarsson

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Brian K Suarez

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Brian T Helfand

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Carlo Zanon

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Donghui Kan

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Droplaug N Magnusdottir

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Eduardo Polo

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P2860

Accurate whole human genome sequencing using reversible terminator chemistry

Genome-wide association study identifies novel breast cancer susceptibility loci

Statistical aspects of the analysis of data from retrospective studies of disease

Multiple newly identified loci associated with prostate cancer susceptibility

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer

Multiple loci identified in a genome-wide association study of prostate cancer

A common inversion under selection in Europeans

Genome-wide association study of prostate cancer identifies a second risk locus at 8q24

Sequence variants at the TERT-CLPTM1L locus associate with many cancer types

Multiple novel prostate cancer predisposition loci confirmed by an international study: the PRACTICAL Consortium.

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10.1038/NG.448

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10

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41

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Unnur Þorsteinsdóttir

Daniel F Gudbjartsson

Lambertus Kiemeney

Johanna Schleutker

Kári Stefánsson

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2009-09-20T00:00:00Z

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26825206

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19767754

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genome-wide association study

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3562712

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