Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet.
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Challenges in Analyzing the Biological Effects of ResveratrolTherapeutic targeting of replicative immortalityJudicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and PerspectivesTimcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses AdipogenesisFrom rapalogs to anti-aging formula.TOR-centric view on insulin resistance and diabetic complications: perspective for endocrinologists and gerontologists.Rapamycin-induced metabolic defects are reversible in both lean and obese miceWeekly administration of rapamycin improves survival and biomarkers in obese male mice on high-fat dietComparison of rapamycin schedules in mice on high-fat diet.Koschei the immortal and anti-aging drugsMetabolic consequences of long-term rapamycin exposure on common marmoset monkeys (Callithrix jacchus)The resveratrol-enriched rice DJ526 boosts motor coordination and physical strength.Rapamycin increases grip strength and attenuates age-related decline in maximal running distance in old low capacity runner rats.High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and VEGFR2.Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance.CDK4/6-inhibiting drug substitutes for p21 and p16 in senescence: duration of cell cycle arrest and MTOR activity determine geroconversion.Dysregulation of the mTOR pathway in p53-deficient mice.Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cellsRapamycin reverses insulin resistance (IR) in high-glucose medium without causing IR in normoglycemic medium.Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles.Immunosuppressants in cancer prevention and therapyMechanism for the synergistic effect of rapamycin and resveratrol on hyperinsulinemia may involve the activation of protein kinase B.Down-regulation of the klf5-c-Myc interaction due to klf5 phosphorylation mediates resveratrol repressing the caveolin-1 transcription through the PI3K/PKD1/Akt pathway.Long-term administration of tacrolimus and everolimus prevents high cholesterol-high fructose-induced steatosis in C57BL/6J mice by inhibiting de-novo lipogenesis.Autophagy in Metabolic Age-Related Human Diseases
P2860
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P2860
Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet.
description
2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
@zh-hk
2013年論文
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2013年論文
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2013年论文
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2013年论文
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name
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@ast
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@en
type
label
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@ast
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@en
prefLabel
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@ast
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@en
P2093
P2860
P356
P1476
Resveratrol potentiates rapamy ...... in male mice on high fat diet.
@en
P2093
G Paszkiewicz
M V Blagosklonny
O V Leontieva
Z N Demidenko
P2860
P356
10.1038/CDDIS.2012.202
P577
2013-01-24T00:00:00Z