Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia.
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Depression as a Glial-Based Synaptic DysfunctionAdenosine A2A receptors modulate acute injury and neuroinflammation in brain ischemiaDo Microglia Default on Network Maintenance in Alzheimer's Disease?The ischemic environment drives microglia and macrophage functionActivation of the Sigma-1 receptor by haloperidol metabolites facilitates brain-derived neurotrophic factor secretion from human astrogliaNeurochemical properties of BDNF-containing neurons projecting to rostral ventromedial medulla in the ventrolateral periaqueductal gray.Activation of microglia bolsters synapse formation.Targeting brain-derived neurotrophic factor in the medial thalamus for the treatment of central poststroke pain in a rodent model.Role of microglia adenosine A(2A) receptors in retinal and brain neurodegenerative diseases.Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levelsATP as a multi-target danger signal in the brain.N-acetylcysteine attenuates lipopolysaccharide-induced impairment in lamination of Ctip2-and Tbr1- expressing cortical neurons in the developing rat fetal brain.Social defeat induces depressive-like states and microglial activation without involvement of peripheral macrophagesMicroglia-derived purines modulate mossy fibre synaptic transmission and plasticity through P2X4 and A1 receptors.Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient micePeripheral nerve injury modulates neurotrophin signaling in the peripheral and central nervous system.May BDNF Be Implicated in the Exercise-Mediated Regulation of Inflammation? Critical Review and Synthesis of Evidence.How does adenosine control neuronal dysfunction and neurodegeneration?Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism.Understanding epigenetic architecture of suicide neurobiology: A critical perspective.Tristetraprolin is a novel regulator of BDNFHaving a Coffee Break: The Impact of Caffeine Consumption on Microglia-Mediated Inflammation in Neurodegenerative Diseases.Microglia modulate respiratory rhythm generation and autoresuscitation.Cortical spreading depolarization stimulates gliogenesis in the rat entorhinal cortex.Huanglian-Jie-Du-Tang Extract Ameliorates Depression-Like Behaviors through BDNF-TrkB-CREB Pathway in Rats with Chronic Unpredictable Stress.Elevated expression of fractalkine (CX3CL1) and fractalkine receptor (CX3CR1) in the dorsal root ganglia and spinal cord in experimental autoimmune encephalomyelitis: implications in multiple sclerosis-induced neuropathic pain.Ribavirin shows immunomodulatory effects on activated microglia.Adenosine A2AR blockade prevents neuroinflammation-induced death of retinal ganglion cells caused by elevated pressure.Role of BDNF/TrkB pathway in the visual system: Therapeutic implications for glaucoma.Adenosine A2A receptor regulation of microglia morphological remodeling-gender bias in physiology and in a model of chronic anxiety.Purinergic system in psychiatric diseases.BDNF at the synapse: why location matters.Critical contribution of adenosine A2A receptors in bone marrow-derived cells to white matter lesions induced by chronic cerebral hypoperfusion.Elevated Pressure Changes the Purinergic System of Microglial Cells.Understanding the Role of Adenosine A2AR Heteroreceptor Complexes in Neurodegeneration and Neuroinflammation.Detrimental Effects of Helium Ion Irradiation on Cognitive Performance and Cortical Levels of MAP-2 in B6D2F1 Mice.Preventive Effect of Low Intensity Pulsed Ultrasound against Experimental Cerebral Ischemia/Reperfusion Injury via Apoptosis Reduction and Brain-derived Neurotrophic Factor Induction.Targeting the CD80/CD86 costimulatory pathway with CTLA4-Ig directs microglia toward a repair phenotype and promotes axonal outgrowth.The Ying and Yang of Adenosine A1 and A2A Receptors on ERK1/2 Activation in a Rat Model of Global Cerebral Ischemia Reperfusion Injury.Depletion of microglia augments the dopaminergic neurotoxicity of MPTP.
P2860
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P2860
Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Activation of microglial cells ...... nd proliferation of microglia.
@ast
Activation of microglial cells ...... nd proliferation of microglia.
@en
type
label
Activation of microglial cells ...... nd proliferation of microglia.
@ast
Activation of microglial cells ...... nd proliferation of microglia.
@en
prefLabel
Activation of microglial cells ...... nd proliferation of microglia.
@ast
Activation of microglial cells ...... nd proliferation of microglia.
@en
P2093
P2860
P356
P1476
Activation of microglial cells ...... nd proliferation of microglia.
@en
P2093
Catarina Gomes
Diana I Rodrigues
Jimmy George
Nélio Gonçalves
Raquel Ferreira
Rodrigo A Cunha
Rui Sanches
P2860
P2888
P356
10.1186/1742-2094-10-16
P577
2013-01-30T00:00:00Z
P5875
P6179
1032129007