p53--a natural cancer killer: structural insights and therapeutic concepts.
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Quaternary structures of tumor suppressor p53 and a specific p53 DNA complexElucidation of Ligand-Dependent Modulation of Disorder-Order Transitions in the Oncoprotein MDM2Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 TetramerThe architecture of functional modules in the Hsp90 co-chaperone Sti1/HopStructures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescueSimulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamicsSolution structure and binding specificity of the p63 DNA binding domainMutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers.BclxL changes conformation upon binding to wild-type but not mutant p53 DNA binding domain.p53 Stabilization induces cell growth inhibition and affects IGF2 pathway in response to radiotherapy in adrenocortical cancer cellsA cell-permeable fusion protein based on Clostridium botulinum C2 toxin for delivery of p53 tumorsuppressor into cancer cells.Competitive binding between dynamic p53 transactivation subdomains to human MDM2 protein: implications for regulating the p53·MDM2/MDMX interaction.Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain.Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis.Physical and functional interactions between human mitochondrial single-stranded DNA-binding protein and tumour suppressor p53Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53.The tumor suppressor p53: from structures to drug discovery.Oral lichen planus and the p53 family: what do we know?Helix-mediated protein--protein interactions as targets for intervention using foldamers.Construction of contiguous tetrasubstituted chiral carbon stereocenters via direct catalytic asymmetric aldol and Mannich-type reactions.2,30-Bis(10H-indole) heterocycles: New p53/MDM2/MDMX antagonists.Efficient delivery of p53 and cytochrome c by supramolecular assembly of a dendritic multi-domain delivery system.DNA damage and DNA damage response in human bronchial epithelial BEAS-2B cells following exposure to 2-nitrobenzanthrone and 3-nitrobenzanthrone: role in apoptosis.Induction of apoptosis promoted by Bang52; a small molecule that downregulates Bcl-x(L).Toxicity of copper(I)-NHC complexes against human tumor cells: induction of cell cycle arrest, apoptosis, and DNA cleavage.Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53.Oligobenzamide proteomimetic inhibitors of the p53-hDM2 protein-protein interaction.Efficient C2 functionalisation of 2H-2-imidazolines.Isomeric control of protein recognition with amino acid- and dipeptide-functionalized gold nanoparticles.
P2860
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P2860
p53--a natural cancer killer: structural insights and therapeutic concepts.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
p53--a natural cancer killer: structural insights and therapeutic concepts.
@ast
p53--a natural cancer killer: structural insights and therapeutic concepts.
@en
type
label
p53--a natural cancer killer: structural insights and therapeutic concepts.
@ast
p53--a natural cancer killer: structural insights and therapeutic concepts.
@en
prefLabel
p53--a natural cancer killer: structural insights and therapeutic concepts.
@ast
p53--a natural cancer killer: structural insights and therapeutic concepts.
@en
P2093
P2860
P356
P1476
p53--a natural cancer killer: structural insights and therapeutic concepts.
@en
P2093
Alexander Dehner
Christian Klein
Horst Kessler
Johannes Buchner
P2860
P304
P356
10.1002/ANIE.200600611
P407
P577
2006-10-01T00:00:00Z