Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?
about
Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft ModelsHypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cellsNew promising drug targets in cancer- and metastasis-initiating cells.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.New advances on critical implications of tumor- and metastasis-initiating cells in cancer progression, treatment resistance and disease recurrenceA genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults.The microenvironment-specific transformation of adult stem cells models malignant triton tumors.Recent advances in cancer stem/progenitor cell research: therapeutic implications for overcoming resistance to the most aggressive cancers.Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development.Cancer associated fibroblasts in hematological malignancies.Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy.CD27 signaling on chronic myelogenous leukemia stem cells activates Wnt target genes and promotes disease progressionABC transporters, neural stem cells and neurogenesis--a different perspective.The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites.Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.Targeting of cancer stem/progenitor cells plus stem cell-based therapies: the ultimate hope for treating and curing aggressive and recurrent cancers.Deconstructing the hematopoietic stem cell niche: revealing the therapeutic potential.Targeting the leukemic stem cell: the Holy Grail of leukemia therapyRecent insights into the molecular mechanisms involved in aging and the malignant transformation of adult stem/progenitor cells and their therapeutic implications.Radionuclide imaging of bone marrow disorders.Stem cells and calcium signaling.STAT5-mediated self-renewal of normal hematopoietic and leukemic stem cells.Wnt/β-catenin signaling in bone marrow niche.Limbal epithelial stem-microenvironmental alteration leads to pterygium development.Activation of Rac1 GTPase promotes leukemia cell chemotherapy resistance, quiescence and niche interaction.Expressions of putative cancer stem cell markers ABCB1, ABCG2, and CD133 are correlated with the degree of differentiation of gastric cancer.A proteomics and transcriptomics approach to identify leukemic stem cell (LSC) markers.High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias.Fine-tuning of hematopoietic stem cell homeostasis: novel role for ubiquitin ligase.On the geometric modeling approach to empirical null distribution estimation for empirical Bayes modeling of multiple hypothesis testingExpression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cellsInflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.Effect of Calcium-Infiltrated Hydroxyapatite Scaffolds on the Hematopoietic Fate of Human Umbilical Vein Endothelial Cells.Icraiin improves Fanconi anemia hematopoietic stem cell function through SIRT6-mediated NF-kappa B inhibition.Differential antigen expression and aberrant signaling via PI3/AKT, MAP/ERK, JAK/STAT, and Wnt/β catenin pathways in Lin-/CD38-/CD34+ cells in acute myeloid leukemia.[Chronic myeloid leukemia stem cells: cross-talk with the niche].Changes of signal transductivity and robustness of gene regulatory network in the carcinogenesis of leukemic subtypes via microarray sample data.
P2860
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P2860
Signaling pathways in self-renewing hematopoietic and leukemic stem cells: do all stem cells need a niche?
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Signaling pathways in self-ren ...... o all stem cells need a niche?
@ast
Signaling pathways in self-ren ...... o all stem cells need a niche?
@en
type
label
Signaling pathways in self-ren ...... o all stem cells need a niche?
@ast
Signaling pathways in self-ren ...... o all stem cells need a niche?
@en
prefLabel
Signaling pathways in self-ren ...... o all stem cells need a niche?
@ast
Signaling pathways in self-ren ...... o all stem cells need a niche?
@en
P2093
P2860
P356
P1476
Signaling pathways in self-ren ...... o all stem cells need a niche?
@en
P2093
Aleksandra Rizo
Edo Vellenga
Gerald de Haan
Jan Jacob Schuringa
P2860
P304
P356
10.1093/HMG/DDL175
P478
15 Spec No 2
P577
2006-10-01T00:00:00Z