Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere. - Wikidata - wikimedia - TriplyDB

Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere.

Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere.

http://www.wikidata.org/entity/Q36600249

about

A new generation of human artificial chromosomes for functional genomics and gene therapy Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells Bi-HAC vector system toward gene and cell therapy Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome A novel system for simultaneous or sequential integration of multiple gene-loading vectors into a defined site of a human artificial chromosome A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function.Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette.Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice.3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function.Moving toward a higher efficiency of microcell-mediated chromosome transfer Protecting a transgene expression from the HAC-based vector by different chromatin insulators.HACking the centromere chromatin code: insights from human artificial chromosomes.Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System.Using human artificial chromosomes to study centromere assembly and function.Core Concept: Human artificial chromosomes offer insights, therapeutic possibilities, and challenges.Interrogating cell division errors using random and chromosome-specific missegregation approaches.Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies.Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies

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P2860

Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere.

http://www.wikidata.org/entity/Q36600249

description

2012 nî lūn-bûn

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Organization of synthetic alph ...... with a conditional centromere.

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Organization of synthetic alph ...... with a conditional centromere.

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Organization of synthetic alph ...... with a conditional centromere.

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Organization of synthetic alph ...... with a conditional centromere.

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Organization of synthetic alph ...... with a conditional centromere.

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Organization of synthetic alph ...... with a conditional centromere.

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ACS Synthetic Biology

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Organization of synthetic alph ...... with a conditional centromere.

@en

P2093

Haiging Fu

http://www.w3.org/2001/XMLSchema#string

Hee-Sheung Lee

http://www.w3.org/2001/XMLSchema#string

Hiroshi Masumoto

http://www.w3.org/2001/XMLSchema#string

Indri Erliandri

http://www.w3.org/2001/XMLSchema#string

Megumi Nakano

http://www.w3.org/2001/XMLSchema#string

Mirit Aladjem

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Mitsuo Oshimura

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Natalay Kouprina

http://www.w3.org/2001/XMLSchema#string

Vladimir Larionov

http://www.w3.org/2001/XMLSchema#string

Yuichi Iida

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P2860

Efficient assembly of de novo human artificial chromosomes from large genomic loci.

Refined human artificial chromosome vectors for gene therapy and animal transgenesis

Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells

Rapid creation of BAC-based human artificial chromosome vectors by transposition with synthetic alpha-satellite arrays

Rapid generation of long synthetic tandem repeats and its application for analysis in human artificial chromosome formation.

Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

From silencing to gene expression: real-time analysis in single cells

Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes.

HAC stability in murine cells is influenced by nuclear localization and chromatin organization.

Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array.

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590-601

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scholarly article

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10.1021/SB3000436

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12

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1

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William Charles Earnshaw

Alexander Samoshkin

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2012-12-01T00:00:00Z

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23411994

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3568986

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