Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells
about
Roles of bioactive sphingolipids in cancer biology and therapeuticsA review of ceramide analogs as potential anticancer agentsTamoxifen regulation of sphingolipid metabolism--Therapeutic implicationsDynamics of ceramide generation and metabolism in response to fenretinide--Diversity within and among leukemiaCeramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance.Evaluation of bioactive sphingolipids in 4-HPR-resistant leukemia cellsGaucher's disease and cancer: a sphingolipid perspectiveGlucose availability and glycolytic metabolism dictate glycosphingolipid levelsApoptotic sphingolipid ceramide in cancer therapy.P-glycoprotein antagonists confer synergistic sensitivity to short-chain ceramide in human multidrug-resistant cancer cells.Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cellsPhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphateAlteration of endoplasmic reticulum lipid rafts contributes to lipotoxicity in pancreatic β-cellsCell motility and drug gradients in the emergence of resistance to chemotherapy.Altered methylation of glucosylceramide synthase promoter regulates its expression and associates with acquired multidrug resistance in invasive ductal breast cancer.Sphingolipids as determinants of apoptosis and chemoresistance in the MCF-7 cell model system.Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer.The role of sphingolipids in drug metabolism and transport.Increased ceramide production sensitizes breast cancer cell response to chemotherapy.Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury.Glucosylceramide synthase promotes Bcl-2 expression via the ERK signaling pathway in the K562/A02 leukemia drug-resistant cell line.FTY720 enhances chemosensitivity of colon cancer cells to doxorubicin and etoposide via the modulation of P-glycoprotein and multidrug resistance protein 1.Sphingolipid abnormalities in cancer multidrug resistance: Chicken or egg?Targeting glucosylceramide synthase downregulates expression of the multidrug resistance gene MDR1 and sensitizes breast carcinoma cells to anticancer drugs.Altered sphingolipid metabolism in patients with metastatic pancreatic cancer.Resveratrol triggers apoptosis through regulating ceramide metabolizing genes in human K562 chronic myeloid leukemia cells.Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer.Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer.C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.Characterization of variants in the glucosylceramide synthase gene and their association with type 1 Gaucher disease severity.The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1).A Comparative Study of Cellular Uptake and Subcellular Localization of Doxorubicin Loaded in Self-Assemblies of Amphiphilic Copolymers with Pendant Dendron by MDA-MB-231 Human Breast Cancer Cells.Gaucher disease and chronic myeloid leukemia: first reported patient receiving enzyme replacement and tyrosine kinase inhibitor therapies simultaneously.γ-Tocotrienol induces apoptosis in pancreatic cancer cells by upregulation of ceramide synthesis and modulation of sphingolipid transport.Ceramide Metabolism Balance, a Multifaceted Factor in Critical Steps of Breast Cancer DevelopmentPolymer-Temozolomide Conjugates as Therapeutics for Treating GlioblastomaFludarabine-resistance associates with ceramide metabolism and leukemia stem cell development in chronic lymphocytic leukemia
P2860
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P2860
Ceramide and glucosylceramide upregulate expression of the multidrug resistance gene MDR1 in cancer cells
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@ast
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@en
type
label
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@ast
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@en
prefLabel
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@ast
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@en
P2093
P2860
P1476
Ceramide and glucosylceramide ...... ance gene MDR1 in cancer cells
@en
P2093
Adam J Kreitenberg
Alicja Bielawska
Armando E Giuliano
Myles C Cabot
Valérie Gouazé-Andersson
P2860
P304
P356
10.1016/J.BBALIP.2007.09.005
P407
P577
2007-11-09T00:00:00Z