Single amino acid substitutions uncouple the DNA binding and strand scission activities of Fok I endonuclease.
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ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaksZinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cellsFokI dimerization is required for DNA cleavageStructure of FokI has implications for DNA cleavageOrigins of Programmable Nucleases for Genome EngineeringStructure of the multimodular endonuclease FokI bound to DNATargeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzymeIn vitro selection of restriction endonucleases by in vitro compartmentalizationChimeric restriction enzymes: what is next?Type II restriction endonucleases--a historical perspective and moreEngineered zinc finger nickases induce homology-directed repair with reduced mutagenic effectsEfficient gene targeting in Drosophila with zinc-finger nucleasesNeSL-1, an ancient lineage of site-specific non-LTR retrotransposons from Caenorhabditis elegans.Folded proteins occur frequently in libraries of random amino acid sequencesThe DNA binding domain of a papillomavirus E2 protein programs a chimeric nuclease to cleave integrated human papillomavirus DNA in HeLa cervical carcinoma cells.Identification of the endonuclease domain encoded by R2 and other site-specific, non-long terminal repeat retrotransposable elements.Overhang polarity of chromosomal double-strand breaks impacts kinetics and fidelity of yeast non-homologous end joiningAn efficient antiviral strategy for targeting hepatitis B virus genome using transcription activator-like effector nucleases.Introduction of asymmetry in the naturally symmetric restriction endonuclease EcoRV to investigate intersubunit communication in the homodimeric protein.Substitutions in conserved dodecapeptide motifs that uncouple the DNA binding and DNA cleavage activities of PI-SceI endonuclease.Identification of TaqI endonuclease active site residues by Fe2+-mediated oxidative cleavage.Binding, bending and cleavage of DNA substrates by the homing endonuclease Pl-SceI.Sequence-specific DNA nicking endonucleases.Genome editing in zebrafish: a practical overview.Engineering nicking enzymes that preferentially nick 5-methylcytosine-modified DNA.Characterization of degQ and degS, Escherichia coli genes encoding homologs of the DegP protease.Illuminating the reaction pathway of the FokI restriction endonuclease by fluorescence resonance energy transfer.DNA looping by two-site restriction endonucleases: heterogeneous probability distributions for loop size and unbinding force.An extraordinary retrotransposon family encoding dual endonucleasesDNA looping by FokI: the impact of synapse geometry on loop topology at varied site orientations.A simple in vivo assay for increased protein solubility.Targeting individual subunits of the FokI restriction endonuclease to specific DNA strands.Mutational analysis of two putative catalytic motifs of the type IV restriction endonuclease Eco57I.Chimeric restriction enzyme: Gal4 fusion to FokI cleavage domain.
P2860
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P2860
Single amino acid substitutions uncouple the DNA binding and strand scission activities of Fok I endonuclease.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Single amino acid substitution ...... ivities of Fok I endonuclease.
@ast
Single amino acid substitution ...... ivities of Fok I endonuclease.
@en
type
label
Single amino acid substitution ...... ivities of Fok I endonuclease.
@ast
Single amino acid substitution ...... ivities of Fok I endonuclease.
@en
prefLabel
Single amino acid substitution ...... ivities of Fok I endonuclease.
@ast
Single amino acid substitution ...... ivities of Fok I endonuclease.
@en
P2860
P356
P1476
Single amino acid substitution ...... tivities of Fok I endonuclease
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.20.9596
P407
P50
P577
1993-10-01T00:00:00Z