Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
about
Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosisEnrichment and analysis of secretory lysosomes from lymphocyte populationsMolecular cloning of an inducible serine esterase gene from human cytotoxic lymphocytesCasein expression in cytotoxic T lymphocytes.Granules of cytolytic T-lymphocytes contain two serine esterases.Stepwise maturation of lytic granules during differentiation and activation of human CD8+ T lymphocytes.Two proteins targeted to the same lytic granule compartment undergo very different posttranslational processing.High activity of N-alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester serine esterase and cytolytic perforin in cloned cell lines is not demonstrable in in-vivo-induced cytotoxic effector cells.Functional channel formation associated with cytotoxic T-cell granules.A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.Natural killer activity of lymphocytic infiltrates in mouse mammary lesionsThe lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments.The Thy-1-bearing cell of murine epidermis. A distinctive leukocyte perhaps related to natural killer cellsInterleukin 2 induction of pore-forming protein gene expression in human peripheral blood CD8+ T cells.Proteoglycans in cell-mediated cytotoxicity. Identification, localization, and exocytosis of a chondroitin sulfate proteoglycan from human cloned natural killer cells during target cell lysis.Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules.Antigen receptor-regulated exocytosis in cytotoxic T lymphocytes.Induction of target cell DNA release by the cytotoxic T lymphocyte granule protease granzyme A.Identification of human neutrophil-derived cathepsin G and azurocidin/CAP37 as chemoattractants for mononuclear cells and neutrophils.The functional basis for hemophagocytic lymphohistiocytosis in a patient with co-inherited missense mutations in the perforin (PFN1) gene.Target cell death triggered by cytotoxic T lymphocytes: a target cell mutant distinguishes passive pore formation and active cell suicide mechanismsMechanism of killing by virus-induced cytotoxic T lymphocytes elicited in vivo.Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T lymphocytes.Intravital imaging of CD8+ T cell function in cancer.Extracellular release of lymphocyte cytolytic pore-forming protein (perforin) after ionophore stimulation.Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules.Identification of aminopeptidase activity in the secretory granules of mouse mast cells.Liposomes as targets for granule cytolysin from cytotoxic large granular lymphocyte tumors.Role of perforin in controlling B-cell hyperactivity and humoral autoimmunity.Appearance of cytolytic granules upon induction of cytolytic activity in CTL-hybrids.Ultrastructural evidence that the granules of human natural killer cell clones store membrane in a nonbilayer phase.Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin).Regulation of perforin lysis: implications for protein disulfide isomerase proteins.Accumulation of natural killer and cytotoxic T large granular lymphocytes in the liver during virus infection.Identification and characterization of a pore-forming protein of human peripheral blood natural killer cells.Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor.Natural killer cells unleashed: Checkpoint receptor blockade and BiKE/TriKE utilization in NK-mediated anti-tumor immunotherapy.
P2860
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P2860
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@ast
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@en
type
label
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@ast
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@en
prefLabel
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@ast
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@en
P2093
P1476
Purification and properties of cytoplasmic granules from cytotoxic rat LGL tumors.
@en
P2093
Henkart MP
Henkart PA
Millard PJ
Reynolds CW
P304
P407
P577
1984-06-01T00:00:00Z