GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells - Wikidata - wikimedia - TriplyDB

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

http://www.wikidata.org/entity/Q36604402

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The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells A mechanosensitive transcriptional mechanism that controls angiogenesis The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes Cutting edge: Type I IFN reverses human Th2 commitment and stability by suppressing GATA3 GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes Regulation of the Adaptive Immune Response by the IκB Family Protein Bcl-3 The effects of TLR activation on T-cell development and differentiation Treatment of allergic asthma: modulation of Th2 cells and their responses Deficiency in Th2 cytokine responses exacerbate orthopoxvirus infection Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune Diseases The differential expression of IL-4 and IL-13 and its impact on type-2 immunity History of interleukin-4 An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but constrains Th17-mediated pathology STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells The transcription factor GATA3 actively represses RUNX3 protein-regulated production of interferon-gamma Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types GATA-binding protein-3 regulates T helper type 2 cytokine and ifng loci through interaction with metastasis-associated protein 2 Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch Differentiation of effector CD4 T cell populations (*)A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner.Highlights of the advances in basic immunology in 2011.Phylogenetic and functional analysis identifies Ets-1 as a novel regulator of the Th2 cytokine gene locus.ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation.The female lower genital tract is a privileged compartment with IL-10 producing dendritic cells and poor Th1 immunity following Chlamydia trachomatis infection.Transcriptional control of impaired Th1 responses in patent lymphatic filariasis by T-box expressed in T cells and suppressor of cytokine signaling genes Th2/1 Hybrid Cells Occurring in Murine and Human Strongyloidiasis Share Effector Functions of Th1 Cells IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells.Helios is associated with CD4 T cells differentiating to T helper 2 and follicular helper T cells in vivo independently of Foxp3 expression.From the cradle to the grave: activities of GATA-3 throughout T-cell development and differentiation.Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.Neurokinin-B transcription in erythroid cells: direct activation by the hematopoietic transcription factor GATA-1.Identification and characterization of noncalcemic, tissue-selective, nonsecosteroidal vitamin D receptor modulators.Common gamma chain (γc) cytokines differentially potentiate TNFR family signaling in antigen-activated CD8(+) T cells

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P2860

GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

http://www.wikidata.org/entity/Q36604402

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells

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I-Cheng Ho

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Morgan L Truitt

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Sung-Yun Pai

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P2860

Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

Activation of the interleukin-5 promoter by cAMP in murine EL-4 cells requires the GATA-3 and CLE0 elements

Inducible gene targeting in mice using the Cre/lox system

Helper T cell differentiation is controlled by the cell cycle

Inhibition of allergic inflammation in a murine model of asthma by expression of a dominant-negative mutant of GATA-3

Critical roles for transcription factor GATA-3 in thymocyte development

Transcription factor GATA-3 is required for development of the T-cell lineage

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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