The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis.
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Functional genomic screen for modulators of ciliogenesis and cilium lengthIdentification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'VPS37 isoforms differentially modulate the ternary complex formation of ALIX, ALG-2, and ESCRT-IHistidine domain-protein tyrosine phosphatase interacts with Grb2 and GrpLLRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular modelMultifaceted Roles of ALG-2 in Ca(2+)-Regulated Membrane TraffickingRoles of dynein and dynactin in early endosome dynamics revealed using automated tracking and global analysisALG-2 interacting protein-X (Alix) is essential for clathrin-independent endocytosis and signalingThe Phe105 Loop of Alix Bro1 Domain Plays a Key Role in HIV-1 ReleaseStructure of the Bro1 Domain Protein BROX and Functional Analyses of the ALIX Bro1 Domain in HIV-1 BuddingTwo Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4BThe Yeast Alix Homolog Bro1 Functions as a Ubiquitin Receptor for Protein Sorting into Multivesicular EndosomesThe Charcot Marie Tooth disease protein LITAF is a zinc-binding monotopic membrane protein.Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions.The multivesicular body is the major internal site of prion conversion.The nucleocapsid region of HIV-1 Gag cooperates with the PTAP and LYPXnL late domains to recruit the cellular machinery necessary for viral buddingHD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.Membrane fission reactions of the mammalian ESCRT pathway.The basic amino acids in the coiled-coil domain of CIN85 regulate its interaction with c-Cbl and phosphatidic acid during epidermal growth factor receptor (EGFR) endocytosis.Endocytic pathway is required for Drosophila Toll innate immune signaling.Viral infection controlled by a calcium-dependent lipid-binding module in ALIX.An ESCRT module is required for neuron pruningTranscriptional Response to Acute Thermal Exposure in Juvenile Chinook Salmon Determined by RNAseq.Structural Study of the HD-PTP Bro1 Domain in a Complex with the Core Region of STAM2, a Subunit of ESCRT-0.The Myopic-Ubpy-Hrs nexus enables endosomal recycling of FrizzledLipid sorting and multivesicular endosome biogenesisA crescent-shaped ALIX dimer targets ESCRT-III CHMP4 filaments.Divergent Bro1 domains share the capacity to bind human immunodeficiency virus type 1 nucleocapsid and to enhance virus-like particle production.Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1.ESCRT & Co.How ubiquitin functions with ESCRTsDifferential requirements of mammalian ESCRTs in multivesicular body formation, virus budding and cell division.Ubiquitin-dependent sorting in endocytosis.Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP.VAMP7 modulates ciliary biogenesis in kidney cells.The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex.The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis.Alix regulates egress of hepatitis B virus naked capsid particles in an ESCRT-independent manner.CIN85 associates with endosomal membrane and binds phosphatidic acid.ALG-2 activates the MVB sorting function of ALIX through relieving its intramolecular interaction.
P2860
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P2860
The Bro1-related protein HD-PTP/PTPN23 is required for endosomal cargo sorting and multivesicular body morphogenesis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@ast
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@en
type
label
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@ast
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@en
prefLabel
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@ast
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@en
P2093
P2860
P356
P1476
The Bro1-related protein HD-PT ...... ivesicular body morphogenesis.
@en
P2093
Aleksandr Mironov
Aurelie Doyotte
Edward McKenzie
Philip Woodman
P2860
P304
P356
10.1073/PNAS.0707601105
P407
P577
2008-04-23T00:00:00Z