ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein.
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Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transportersVandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport functionPresent and future evolution of advanced breast cancer therapy.Effects of Astragalus polysaccharides on P-glycoprotein efflux pump function and protein expression in H22 hepatoma cells in vitroPhase I and pharmacokinetic study of pazopanib and lapatinib combination therapy in patients with advanced solid tumors.Vandetanib mediates anti-leukemia activity by multiple mechanisms and interacts synergistically with DNA damaging agents.The 100 most-cited articles on cardiovascular diseases from Mainland ChinaNeratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo.Astragalus polysaccharides can regulate cytokine and P-glycoprotein expression in H22 tumor-bearing mice.Effect of ceritinib (LDK378) on enhancement of chemotherapeutic agents in ABCB1 and ABCG2 overexpressing cells in vitro and in vivo.Reversing multidrug resistance by tyrosine kinase inhibitorsNovel targeted agents for the treatment of advanced breast cancer.Computational and mechanistic studies on the effect of galactoxyloglucan: Imatinib nanoconjugate in imatinib resistant K562 cells.Inhibition of sodium-independent and sodium-dependent nucleobase transport activities by tyrosine kinase inhibitors.Influence of the multidrug transporter P-glycoprotein on the intracellular pharmacokinetics of vandetanib.Euphorbia factor L1 reverses ABCB1-mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion.Tyrosine kinase inhibitors enhanced the efficacy of conventional chemotherapeutic agent in multidrug resistant cancer cells.Contribution of tumor endothelial cells to drug resistance: anti-angiogenic tyrosine kinase inhibitors act as p-glycoprotein antagonists.Tumor targeting with pH-responsive poly(2-oxazoline)-based nanogels for metronomic doxorubicin treatment.Effect of five novel 5-substituted tetrandrine derivatives on P-glycoprotein-mediated inhibition and transport in Caco-2 cells
P2860
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P2860
ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@ast
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@en
type
label
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@ast
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@en
prefLabel
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@ast
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@en
P2860
P356
P1476
ZD6474 reverses multidrug resi ...... he function of P-glycoprotein.
@en
P2860
P2888
P304
P356
10.1038/SJ.BJC.6603985
P407
P577
2007-10-02T00:00:00Z
P5875
P6179
1023943894