O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts
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Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapyFluorogenic Real-Time Reporters of DNA Repair by MGMT, a Clinical Predictor of Antitumor Drug ResponseTemozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada - Clinical Trials Group (NCIC-CTG).Tumor O(6)-methylguanine-DNA methyltransferase inactivation by oral lomeguatrib.DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapyDownregulation of hPMC2 imparts chemotherapeutic sensitivity to alkylating agents in breast cancer cellsO6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomasNF-κB is activated in response to temozolomide in an AKT-dependent manner and confers protection against the growth suppressive effect of the drug.Live and let die: in vivo selection of gene-modified hematopoietic stem cells via MGMT-mediated chemoprotectionGlioblastoma multiforme therapy and mechanisms of resistance.Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics.Chemotherapeutic resistance in anaplastic astrocytoma cell lines treated with a temozolomide-lomeguatrib combination.Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals.Predictive value of MGMT, hMLH1, hMSH2 and BRCA1 protein expression for pathological complete response to neoadjuvant chemotherapy in basal-like breast cancer patients.Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.Renal cell carcinoma does not express argininosuccinate synthetase and is highly sensitive to arginine deprivation via arginine deiminase.
P2860
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P2860
O6-(4-bromothenyl)guanine reverses temozolomide resistance in human breast tumour MCF-7 cells and xenografts
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@ast
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@en
type
label
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@ast
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@en
prefLabel
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@ast
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@en
P2093
P2860
P356
P1476
O6-(4-bromothenyl)guanine reve ...... our MCF-7 cells and xenografts
@en
P2093
A J Watson
G P Margison
R S McElhinney
T B H McMurry
P2860
P2888
P304
P356
10.1038/SJ.BJC.6602833
P407
P577
2005-11-01T00:00:00Z