Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development. - Wikidata - wikimedia - TriplyDB

Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development.

Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development.

http://www.wikidata.org/entity/Q36620077

about

Transforming growth factor-β suppresses metastasis in a subset of human colon carcinoma cells In-depth genomic data analyses revealed complex transcriptional and epigenetic dysregulations of BRAFV600E in melanoma.Enhanced tumorigenesis and reduced transforming growth factor-beta type II receptor in lung tumors from mice with reduced gene dosage of transforming growth factor-beta1.TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study.Histone deacetylase inhibitor belinostat represses survivin expression through reactivation of transforming growth factor beta (TGFbeta) receptor II leading to cancer cell death.Associated changes of lipid peroxidation and transforming growth factor beta1 levels in human colon cancer during tumour progression.Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells.An epigenetic auto-feedback loop regulates TGF-β type II receptor expression and function in NSCLC.Clinical applications of gene expression in colorectal cancer.Overexpression of FOXG1 contributes to TGF-beta resistance through inhibition of p21WAF1/CIP1 expression in ovarian cancer Mammary Gland Involution Provides a Unique Model to Study the TGF-β Cancer Paradox.Dietary fiber enhances TGF-β signaling and growth inhibition in the gut.Bombesin enhances TGF-beta growth inhibitory effect through apoptosis induction in intestinal epithelial cells.Ciprofloxacin decreases survival in HT-29 cells via the induction of TGF-beta1 secretion and enhances the anti-proliferative effect of 5-fluorouracil Unique characteristics of rectal carcinoma cell lines derived from invasive carcinomas in ulcerative colitis patients.TIMP-1 expression in human colorectal cancer is associated with TGF-B1, LOXL2, INHBA1, TNF-AIP6 and TIMP-2 transcript profiles.Conditional loss of TGF-beta signalling leads to increased susceptibility to gastrointestinal carcinogenesis in mice.YY1 Over-expression in human brain gliomas and meningiomas correlates with TGF-beta1, IGF-1 and FGF-2 mRNA levels."Vessels in the Storm": Searching for Prognostic and Predictive Angiogenic Factors in Colorectal Cancer.Prognostic significance of Cytokeratin 20-positive lymph node vascular endothelial growth factor A mRNA and chromodomain helicase DNA binding protein 4 in pN0 colorectal cancer patients.Steady state levels of transforming growth factor-beta1 and -beta2 mRNA and protein expression are elevated in colonic tumors in vivo irrespective of dietary lipids intervention.Analysis of transforming growth factor β receptor expression and signaling in higher grade meningiomas.

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P2860

Down-regulation of TGF-beta receptors in human colorectal cancer: implications for cancer development.

http://www.wikidata.org/entity/Q36620077

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P2860

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity

Inhibin antagonizes inhibition of liver cell growth by activin by a dominant-negative mechanism

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

Genomic structure and cloned cDNAs predict that four variants in the kinase domain of serine/threonine kinase receptors arise by alternative splicing and poly(A) addition

Characterization of type I receptors for transforming growth factor-beta and activin

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice

Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes

Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor

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colorectal cancer

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