Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. - Wikidata - wikimedia - TriplyDB

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease.

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease.

http://www.wikidata.org/entity/Q36622356

about

Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture Differential Co-Expression between α-Synuclein and IFN-γ Signaling Genes across Development and in Parkinson’s Disease Genetic perspective on the role of the autophagy-lysosome pathway in Parkinson disease The prediagnostic phase of Parkinson's disease Usefulness of Genetic Testing in PD and PD Trials: A Balanced Review Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease Host genetics and viral load in primary HIV-1 infection: clear evidence for gene by sex interactions A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis.Risk prediction for complex diseases: application to Parkinson disease.Genome-wide estimate of the heritability of Multiple System Atrophy Identification of genetic modifiers of age-at-onset for familial Parkinson's disease Identifying rare and common disease associated variants in genomic data using Parkinson's disease as a model.Additional rare variant analysis in Parkinson's disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance.Estimating the heritability of colorectal cancer.Genome-wide mapping of IBD segments in an Ashkenazi PD cohort identifies associated haplotypes.Missing heritability of common diseases and treatments outside the protein-coding exome.The pallidopyramidal syndromes: nosology, aetiology and pathogenesis.Genotype-environment correlation in the era of DNA Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology Genetic markers of Restless Legs Syndrome in Parkinson disease Estimation of heritability for nine common cancers using data from genome-wide association studies in Chinese population.Variants in GBA, SNCA, and MAPT influence Parkinson disease risk, age at onset, and progression.Polygenic risk of Parkinson disease is correlated with disease age at onset.A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases.Genotype and age at Parkinson disease diagnosis.Resequencing analysis of five Mendelian genes and the top genes from genome-wide association studies in Parkinson's Disease.Association Analysis of Proteasome Subunits and Transporter Associated with Antigen Processing on Chinese Patients with Parkinson's Disease A genome-wide association study of myasthenia gravis Genome-Wide Estimates of Heritability for Social Demographic Outcomes The Evolution of Genetics: Alzheimer's and Parkinson's Diseases.Mendelian Randomization - the Key to Understanding Aspects of Parkinson's Disease Causation?Morphometricity as a measure of the neuroanatomical signature of a trait Assessment of Parkinson's disease risk loci in Greece Genetic comorbidities in Parkinson's disease.Multiple system atrophy: the application of genetics in understanding etiology.Genetic insights into sporadic Parkinson's disease pathogenesis.Discovery and functional prioritization of Parkinson's disease candidate genes from large-scale whole exome sequencing.SNP-based heritability estimates of the personality dimensions and polygenic prediction of both neuroticism and major depression: findings from CONVERGE.Association studies of sporadic Parkinson's disease in the genomic era.

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Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease.

http://www.wikidata.org/entity/Q36622356

description

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2012年论文

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2012年论文

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2012年论文

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name

Using genome-wide complex trai ...... ility' in Parkinson's disease.

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Human Molecular Genetics

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Using genome-wide complex trai ...... ility' in Parkinson's disease.

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Claudia Schulte

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Dena G Hernandez

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Francesco Bettella

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Hreinn Stefánsson

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J Raphael Gibbs

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Javier Simón-Sánchez

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Kari Majamaa

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Manu Sharma

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Margaux F Keller

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Michael A Nalls

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P2860

A two-stage meta-analysis identifies several new loci for Parkinson's disease

Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease

Finding the missing heritability of complex diseases

Are rare variants responsible for susceptibility to complex diseases?

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study

Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes

Genome-wide association study reveals genetic risk underlying Parkinson's disease

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

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4996-5009

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scholarly article

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10.1093/HMG/DDS335

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22

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21

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Nicholas W. Wood

Laura L. Kilarski

Andrew Singleton

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2012-08-13T00:00:00Z

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230670809

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22892372

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Parkinson's disease

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3576713

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