The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.
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A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type-specific manner and Is recruited to the nucleus after infectionHerpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathwaysHerpes simplex virus IE63 (ICP27) protein interacts with spliceosome-associated protein 145 and inhibits splicing prior to the first catalytic stepMolecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine.mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway.APOBEC1-mediated editing and attenuation of herpes simplex virus 1 DNA indicate that neurons have an antiviral role during herpes simplex encephalitisShutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesA role for cytoplasmic PML in cellular resistance to viral infectionAnalysis of the phosphorylation sites of herpes simplex virus type 1 regulatory protein ICP27.ICP27 phosphorylation site mutants are defective in herpes simplex virus 1 replication and gene expression.ICP27 phosphorylation site mutants display altered functional interactions with cellular export factors Aly/REF and TAP/NXF1 but are able to bind herpes simplex virus 1 RNAICP27 recruits Aly/REF but not TAP/NXF1 to herpes simplex virus type 1 transcription sites although TAP/NXF1 is required for ICP27 export.Control of VP16 translation by the herpes simplex virus type 1 immediate-early protein ICP27.Purification and characterization of a cellular protein that binds to the downstream activation sequence of the strict late UL38 promoter of herpes simplex virus type 1The human herpesvirus 8 homolog of Epstein-Barr virus SM protein (KS-SM) is a posttranscriptional activator of gene expressionHerpesvirus mRNAs are sorted for export via Crm1-dependent and -independent pathwaysHerpes simplex virus ICP27 induces cytoplasmic accumulation of unspliced polyadenylated alpha-globin pre-mRNA in infected HeLa cells.Processing of alpha-globin and ICP0 mRNA in cells infected with herpes simplex virus type 1 ICP27 mutants.The conserved carboxyl-terminal half of herpes simplex virus type 1 regulatory protein ICP27 is dispensable for viral growth in the presence of compensatory mutationsIdentification of an export control sequence and a requirement for the KH domains in ICP27 from herpes simplex virus type 1Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.Induction and prevention of apoptosis in human HEp-2 cells by herpes simplex virus type 1.Epstein-Barr virus SM protein interacts with mRNA in vivo and mediates a gene-specific increase in cytoplasmic mRNA.Herpes simplex virus type 1 2-kilobase latency-associated transcript intron associates with ribosomal proteins and splicing factors.Translational control of viral gene expression in eukaryotesHerpes simplex virus ICP27 protein provides viral mRNAs with access to the cellular mRNA export pathway.UL54-null pseudorabies virus is attenuated in mice but productively infects cells in cultureMapping of functional regions in the amino-terminal portion of the herpes simplex virus ICP27 regulatory protein: importance of the leucine-rich nuclear export signal and RGG Box RNA-binding domain.mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.The patterns of accumulation of cellular RNAs in cells infected with a wild-type and a mutant herpes simplex virus 1 lacking the virion host shutoff gene.ICP27 selectively regulates the cytoplasmic localization of a subset of viral transcripts in herpes simplex virus type 1-infected cellsFunctional analysis of Epstein-Barr virus SM protein: identification of amino acids essential for structure, transactivation, splicing inhibition, and virion productionFunctional genomic analysis of herpes simplex virus type 1 counteraction of the host innate response.Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 geneICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motifActivation and evasion of innate antiviral immunity by herpes simplex virusHerpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma-associated herpesvirus ORF57 protein and host pre-mRNA metabolismHerpes simplex virus eliminates host mitochondrial DNA.
P2860
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P2860
The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The herpes simplex virus regul ...... mRNA levels during infection.
@ast
The herpes simplex virus regul ...... mRNA levels during infection.
@en
type
label
The herpes simplex virus regul ...... mRNA levels during infection.
@ast
The herpes simplex virus regul ...... mRNA levels during infection.
@en
prefLabel
The herpes simplex virus regul ...... mRNA levels during infection.
@ast
The herpes simplex virus regul ...... mRNA levels during infection.
@en
P2860
P1433
P1476
The herpes simplex virus regul ...... mRNA levels during infection.
@en
P2093
M A Hardwicke
R M Sandri-Goldin
P2860
P304
P407
P577
1994-08-01T00:00:00Z