DNA binding specificity of the bovine papillomavirus E1 protein is determined by sequences contained within an 18-base-pair inverted repeat element at the origin of replication.
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Cellular topoisomerase I modulates origin binding by bovine papillomavirus type 1 E1.Transient viral DNA replication and repression of viral transcription are supported by the C-terminal domain of the bovine papillomavirus type 1 E1 protein.Characterization of the DNA-binding domain of the bovine papillomavirus replication initiator E1.A C-terminal helicase domain of the human papillomavirus E1 protein binds E2 and the DNA polymerase alpha-primase p68 subunit.The E1 initiator recognizes multiple overlapping sites in the papillomavirus origin of DNA replication.Sequential and ordered assembly of E1 initiator complexes on the papillomavirus origin of DNA replication generates progressive structural changes related to melting.Replication and partitioning of papillomavirus genomes.Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteinsE1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication.Bovine papillomavirus E1 protein binds specifically DNA polymerase alpha but not replication protein ABovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro.Mutational analysis of the 18-base-pair inverted repeat element at the bovine papillomavirus origin of replication: identification of critical sequences for E1 binding and in vivo replicationIsolation of an amino-terminal region of bovine papillomavirus type 1 E1 protein that retains origin binding and E2 interaction capacity.Functional interactions between papillomavirus E1 and E2 proteins.Bovine papillomavirus type 1 E1 and simian virus 40 large T antigen share regions of sequence similarity required for multiple functions.The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID.The E1 proteins.Two E2 binding sites alone are sufficient to function as the minimal origin of replication of human papillomavirus type 18 DNA.Identification of a short, hydrophilic amino acid sequence critical for origin recognition by the bovine papillomavirus E1 protein.A fifteen-amino-acid peptide inhibits human papillomavirus E1-E2 interaction and human papillomavirus DNA replication in vitro.Distinct roles of two binding sites for the bovine papillomavirus (BPV) E2 transactivator on BPV DNA replication.Regulation of bovine papillomavirus replicative helicase e1 by the ubiquitin-proteasome pathway.cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin.E1 recognition sequences in the bovine papillomavirus type 1 origin of DNA replication: interaction between half sites of the inverted repeats.Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus.Structure-based mutational analysis of the bovine papillomavirus E1 helicase domain identifies residues involved in the nonspecific DNA binding activity required for double trimer formation.Bovine papillomavirus replicative helicase E1 is a target of the ubiquitin ligase APC.Co-operative interaction between the initiator E1 and the transcriptional activator E2 is required for replicator specific DNA replication of bovine papillomavirus in vivo and in vitro.ATP-dependent minor groove recognition of TA base pairs is required for template melting by the E1 initiator protein.Mutations in Sensor 1 and Walker B in the bovine papillomavirus E1 initiator protein mimic the nucleotide-bound stateNucleocytoplasmic shuttling of bovine papillomavirus E1 helicase downregulates viral DNA replication in S phase.
P2860
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P2860
DNA binding specificity of the bovine papillomavirus E1 protein is determined by sequences contained within an 18-base-pair inverted repeat element at the origin of replication.
description
1994 nî lūn-bûn
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1994年の論文
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1994年論文
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1994年論文
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1994年論文
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name
DNA binding specificity of the ...... at the origin of replication.
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DNA binding specificity of the ...... at the origin of replication.
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type
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DNA binding specificity of the ...... at the origin of replication.
@ast
DNA binding specificity of the ...... at the origin of replication.
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DNA binding specificity of the ...... at the origin of replication.
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DNA binding specificity of the ...... at the origin of replication.
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P2093
P2860
P1433
P1476
DNA binding specificity of the ...... t at the origin of replication
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P2093
P2860
P304
P407
P577
1994-02-01T00:00:00Z