Selective targeting of ITK blocks multiple steps of HIV replication.
about
Dynamics of the Tec-family tyrosine kinase SH3 domains.The accessory factor Nef links HIV-1 to Tec/Btk kinases in an Src homology 3 domain-dependent manner.Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptorsCD28 and ITK signals regulate autoreactive T cell trafficking.Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs.Combinatorial signals from CD28 differentially regulate human immunodeficiency virus transcription in T cellsInterleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases.Identification of Hck inhibitors as hits for the development of antileukemia and anti-HIV agents.Itk: the rheostat of the T cell response.Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cellsThe trinity of the cortical actin in the initiation of HIV-1 infectionInterleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkIbrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytesProteasome inactivation promotes p38 mitogen-activated protein kinase-dependent phosphatidylinositol 3-kinase activation and increases interleukin-8 production in retinal pigment epithelial cells.Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases.The adaptor protein SLP-76 regulates HIV-1 release and cell-to-cell transmission in T cells.Itk inhibitors: a patent review.TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.Integrin signalling and function in immune cells.Regulation of T-cell responses and disease by tec kinase Itk.Ibrutinib-A double-edge sword in cancer and autoimmune disorders.The Src kinase Lck facilitates assembly of HIV-1 at the plasma membrane.IL-2-inducible T-cell kinase (ITK) finds another (dance) partner...TFII-IIL-2 Inducible Kinase ITK is Critical for HIV-1 Infection of Jurkat T-cells.A single β-octyl glucoside molecule induces HIV-1 Nef dimer formation in the absence of partner protein binding.Inhibition of Human Immunodeficiency Virus Type 1 Entry by a Keggin Polyoxometalate.
P2860
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P2860
Selective targeting of ITK blocks multiple steps of HIV replication.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Selective targeting of ITK blocks multiple steps of HIV replication.
@ast
Selective targeting of ITK blocks multiple steps of HIV replication.
@en
type
label
Selective targeting of ITK blocks multiple steps of HIV replication.
@ast
Selective targeting of ITK blocks multiple steps of HIV replication.
@en
prefLabel
Selective targeting of ITK blocks multiple steps of HIV replication.
@ast
Selective targeting of ITK blocks multiple steps of HIV replication.
@en
P2093
P2860
P356
P1476
Selective targeting of ITK blocks multiple steps of HIV replication
@en
P2093
Avery August
Craig J Thomas
Gillian M Schiralli
Jian-Kang Jiang
Julie A Readinger
Pamela L Schwartzberg
P2860
P304
P356
10.1073/PNAS.0709659105
P407
P577
2008-04-28T00:00:00Z