Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques.
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The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremiaVirus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infectionTemporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndromeTargeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunizationEx vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotypeGagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivoCD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.Molecular evolution of human immunodeficiency virus type 1 upon transmission between human leukocyte antigen disparate donor-recipient pairs.In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain.Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication.Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequencesEffective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Natural infection of a household pet red-capped mangabey (Cercocebus torquatus torquatus) with a new simian immunodeficiency virusViral genetic evolution in macaques infected with molecularly cloned simian immunodeficiency virus correlates with the extent of persistent viremia.Shortening of the symptom-free period in rhesus macaques is associated with decreasing nonsynonymous variation in the env variable regions of simian immunodeficiency virus SIVsm during passage.Temporal analyses of virus replication, immune responses, and efficacy in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.Infection with HIV-1.Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: evidence for an influence on disease progression.Wide range of viral load in healthy african green monkeys naturally infected with simian immunodeficiency virus.Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection.Use of major histocompatibility complex class I/peptide/beta2M tetramers to quantitate CD8(+) cytotoxic T lymphocytes specific for dominant and nondominant viral epitopes in simian-human immunodeficiency virus-infected rhesus monkeysPartial regulatory T cell depletion prior to acute feline immunodeficiency virus infection does not alter disease pathogenesisCD8(+) lymphocytes from simian immunodeficiency virus-infected rhesus macaques recognize 14 different epitopes bound by the major histocompatibility complex class I molecule mamu-A*01: implications for vaccine design and testing.Membrane-fusing capacity of the human immunodeficiency virus envelope proteins determines the efficiency of CD+ T-cell depletion in macaques infected by a simian-human immunodeficiency virusInduction of neutralizing antibodies and gag-specific cellular immune responses to an R5 primary isolate of human immunodeficiency virus type 1 in rhesus macaques.Longitudinal assessment of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon responses during the first year of life in HIV-1-infected infants.Quantification of the relative importance of CTL, B cell, NK cell, and target cell limitation in the control of primary SIV-infectionCD8+ T-lymphocyte response to major immunodominant epitopes after vaginal exposure to simian immunodeficiency virus: too late and too little.The role of MHC class I allele Mamu-A*07 during SIV(mac)239 infectionIncreased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus.High levels of viral replication contrast with only transient changes in CD4(+) and CD8(+) cell numbers during the early phase of experimental infection with simian immunodeficiency virus SIVmnd-1 in Mandrillus sphinx.Compartmentalization of simian immunodeficiency virus replication within secondary lymphoid tissues of rhesus macaques is linked to disease stage and inversely related to localization of virus-specific CTL.Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers.In vitro and animal models of human immunodeficiency virus infection of the central nervous systemnef gene is required for robust productive infection by simian immunodeficiency virus of T-cell-rich paracortex in lymph nodes.The relationship between simian immunodeficiency virus RNA levels and the mRNA levels of alpha/beta interferons (IFN-alpha/beta) and IFN-alpha/beta-inducible Mx in lymphoid tissues of rhesus macaques during acute and chronic infection.Clinical use of quantitative molecular methods in studying human immunodeficiency virus type 1 infection.Loss of naïve cells accompanies memory CD4+ T-cell depletion during long-term progression to AIDS in Simian immunodeficiency virus-infected macaques.An acutely lethal simian immunodeficiency virus stimulates expansion of V beta 7- and V beta 14-expressing T lymphocytes.Expression of cytokine mRNA in lentivirus-induced arthritis
P2860
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P2860
Immunopathogenic events in acute infection of rhesus monkeys with simian immunodeficiency virus of macaques.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@ast
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@en
type
label
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@ast
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@en
prefLabel
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@ast
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@en
P2093
P2860
P1433
P1476
Immunopathogenic events in acu ...... odeficiency virus of macaques.
@en
P2093
B J Ransil
K A Reimann
K Tenner-Racz
N L Letvin
Y Yasutomi
P2860
P304
P407
P577
1994-04-01T00:00:00Z