Eukaryotic Y-family polymerases bypass a 3-methyl-2'-deoxyadenosine analog in vitro and methyl methanesulfonate-induced DNA damage in vivo - Wikidata - wikimedia - TriplyDB

Eukaryotic Y-family polymerases bypass a 3-methyl-2'-deoxyadenosine analog in vitro and methyl methanesulfonate-induced DNA damage in vivo

Eukaryotic Y-family polymerases bypass a 3-methyl-2'-deoxyadenosine analog in vitro and methyl methanesulfonate-induced DNA damage in vivo

http://www.wikidata.org/entity/Q36633158

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Real-time imaging of DNA damage in yeast cells using ultra-short near-infrared pulsed laser irradiation An unprecedented nucleic acid capture mechanism for excision of DNA damage An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion Synthesis SHPRH and HLTF act in a damage-specific manner to coordinate different forms of postreplication repair and prevent mutagenesis.Influence of local sequence context on damaged base conformation in human DNA polymerase iota: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion Increasing occurrences and functional roles for high energy purine-pyrimidine base-pairs in nucleic acids Variations on a theme: eukaryotic Y-family DNA polymerases Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota.XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine.Selection of dinB alleles suppressing survival loss upon dinB overexpression in Escherichia coli.Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization.Recent advances in the structural mechanisms of DNA glycosylases A historical account of Hoogsteen base-pairs in duplex DNA.Escherichia coli YafP protein modulates DNA damaging property of the nitroaromatic compounds 3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro.Pre-steady state kinetic studies show that an abasic site is a cognate lesion for the yeast Rev1 protein.DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida Repair of 3-methyladenine and abasic sites by base excision repair mediates glioblastoma resistance to temozolomide A single residue unique to DinB-like proteins limits formation of the polymerase IV multiprotein complex in Escherichia coli.Synthesis and characterization of DNA minor groove binding alkylating agents The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing?High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells.Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair.PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome.DNA polymerase kappa protects human cells against MMC-induced genotoxicity through error-free translesion DNA synthesis Minor Groove 3-Deaza-Adenosine Analogues: Synthesis and Bypass in Translesion DNA Synthesis.Minimally cytotoxic doses of temozolomide produce radiosensitization in human glioblastoma cells regardless of MGMT expression.Thermodynamic characterization of DNA with 3-deazaadenine and 3-methyl-3-deazaadenine substitutions: the effect of placing a hydrophobic group in the minor groove of DNA.Aberrant Kynurenine Signaling Modulates DNA Replication Stress Factors and Promotes Genomic Instability in Gliomas.Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage.The DinB•RecA complex of Escherichia coli mediates an efficient and high-fidelity response to ubiquitous alkylation lesions.Non-bulky Lesions in Human DNA: the Ways of Formation, Repair, and Replication.Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity.

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Eukaryotic Y-family polymerases bypass a 3-methyl-2'-deoxyadenosine analog in vitro and methyl methanesulfonate-induced DNA damage in vivo

http://www.wikidata.org/entity/Q36633158

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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Nucleic Acids Research

P1476

Eukaryotic Y-family polymerase ...... ate-induced DNA damage in vivo

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P2093

Brian S Plosky

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David A Berry

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Ekaterina G Frank

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Graham P Vennall

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John P McDonald

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Roger Woodgate

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P2860

Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions

poliota, a remarkably error-prone human DNA polymerase

Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG

Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication

MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway

Cloning and expression in Escherichia coli of a gene for an alkylbase DNA glycosylase from Saccharomyces cerevisiae; a homologue to the bacterial alkA gene.

Thymine-thymine dimer bypass by yeast DNA polymerase zeta.

The Saccharomyces cerevisiae RAD30 gene, a homologue of Escherichia coli dinB and umuC, is DNA damage inducible and functions in a novel error-free postreplication repair mechanism

Identification of APN2, the Saccharomyces cerevisiae homolog of the major human AP endonuclease HAP1, and its role in the repair of abasic sites.

Novel human and mouse homologs of Saccharomyces cerevisiae DNA polymerase eta

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2152-2162

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10.1093/NAR/GKN058

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7

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36

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2008-02-14T00:00:00Z

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5571464

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18281311

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2367705

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