Progress in the development of potent bombesin receptor antagonists.
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International Union of Pharmacology. LXVIII. Mammalian bombesin receptors: nomenclature, distribution, pharmacology, signaling, and functions in normal and disease statesInsights into bombesin receptors and ligands: Highlighting recent advancesBicarbonate and fluid secretion evoked by cholecystokinin, bombesin and acetylcholine in isolated guinea-pig pancreatic ductsMolecular basis for selectivity of high affinity peptide antagonists for the gastrin-releasing peptide receptorActivation of neuromedin B-preferring bombesin receptors on rat glioblastoma C-6 cells increases cellular Ca2+ and phosphoinositidesA combinatorial peptoid library for the identification of novel MSH and GRP/bombesin receptor ligands.Tyrosine 220 in the 5th transmembrane domain of the neuromedin B receptor is critical for the high selectivity of the peptoid antagonist PD168368.Bombesin receptor subtype 3 as a potential target for obesity and diabetes.A rhesus monkey model to characterize the role of gastrin-releasing peptide (GRP) in lung development. Evidence for stimulation of airway growthDiscovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology compared with other mammalian bombesin receptors.Ability of various bombesin receptor agonists and antagonists to alter intracellular signaling of the human orphan receptor BRS-3.Peptides as receptor ligand drugs and their relationship to G-coupled signal transduction.Bombesin receptor-mediated imaging and cytotoxicity: review and current statusNeurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation.Regulation of gastric function by endogenous gastrin releasing peptide in humans: studies with a specific gastrin releasing peptide receptor antagonist.Design, synthesis, and in vitro evaluation of cytotoxic analogs of bombesin-like peptides containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin.Development of potent gastrin-releasing peptide antagonists having a D-Pro-psi(CH2NH)-Phe-NH2 C terminusThe molecular basis for high affinity of a universal ligand for human bombesin receptor (BnR) family members.Depression of primary afferent-evoked responses by GR71251 in the isolated spinal cord of the neonatal rat.Function of non-visual arrestins in signaling and endocytosis of the gastrin-releasing peptide receptor (GRP receptor).Bombesin family receptor and ligand gene expression in human colorectal cancer and normal mucosa.CCKB/gastrin receptor antagonists: recent advances and potential uses in gastric secretory disordersComparative pharmacology of bombesin receptor subtype-3, nonpeptide agonist MK-5046, a universal peptide agonist, and peptide antagonist Bantag-1 for human bombesin receptorsCharacterization of putative GRP- and NMB-receptor antagonist's interaction with human receptors.Metabolism of the broad-spectrum neuropeptide growth factor antagonist: [D-Arg1, D-Phe5, D-Trp7,9, Leu11]-substance P.Bombesin-like peptides in the regulation of ingestive behavior.Therapeutic use and perspectives of synthetic peptides in oncology.A human gastric cancer cell line possesses a functional receptor for gastrin-releasing peptide.Down-regulation of bombesin binding to guinea-pig pancreatic acinar cells during homologous desensitization.Evaluation of radiolabelled bombesin analogues for receptor-targeted scintigraphy and radiotherapy.Gastrin-releasing peptide receptors in non-neoplastic and neoplastic human breast.Bombesin-like peptides depolarize rat hippocampal interneurones through interaction with subtype 2 bombesin receptors.Quisqualate-stimulated phosphatidylinositol breakdown in rat cerebellar membranes.
P2860
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P2860
Progress in the development of potent bombesin receptor antagonists.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Progress in the development of potent bombesin receptor antagonists.
@ast
Progress in the development of potent bombesin receptor antagonists.
@en
type
label
Progress in the development of potent bombesin receptor antagonists.
@ast
Progress in the development of potent bombesin receptor antagonists.
@en
prefLabel
Progress in the development of potent bombesin receptor antagonists.
@ast
Progress in the development of potent bombesin receptor antagonists.
@en
P1476
Progress in the development of potent bombesin receptor antagonists.
@en
P2093
P356
10.1016/0165-6147(91)90483-9
P577
1991-01-01T00:00:00Z