c-Cbl, a ubiquitin E3 ligase that targets active β-catenin: a novel layer of Wnt signaling regulation.
about
The ubiquitin ligase RNF220 enhances canonical Wnt signaling through USP7-mediated deubiquitination of β-cateninThe regulation of β-catenin activity and function in cancer: therapeutic opportunitiesTumour suppressor TRIM33 targets nuclear β-catenin degradationCD4 T-cell transcriptome analysis reveals aberrant regulation of STAT3 and Wnt signaling pathways in rheumatoid arthritis: evidence from a case-control study.The c-Cbl ubiquitin ligase regulates nuclear β-catenin and angiogenesis by its tyrosine phosphorylation mediated through the Wnt signaling pathway.Molecular pathways: turning proteasomal protein degradation into a unique treatment approach.Ubiquitin-specific protease 4 controls metastatic potential through β-catenin stabilization in brain metastatic lung adenocarcinomaAn oxygen-insensitive Hif-3α isoform inhibits Wnt signaling by destabilizing the nuclear β-catenin complex.c-Cbl mediates the degradation of tumorigenic nuclear β-catenin contributing to the heterogeneity in Wnt activity in colorectal tumors.Cool-1-mediated inhibition of c-Cbl modulates multiple critical properties of glioblastomas, including the ability to generate tumors in vivo.Molecular dissection of a rice microtubule-associated RING finger protein and its potential role in salt tolerance in Arabidopsis.c-CBL regulates melanoma proliferation, migration, invasion and the FAK-SRC-GRB2 nexus.TRIM22 confers poor prognosis and promotes epithelial-mesenchymal transition through regulation of AKT/GSK3β/β-catenin signaling in non-small cell lung cancer.Berberine binds RXRα to suppress β-catenin signaling in colon cancer cells.Identifying the substrate proteins of U-box E3s E4B and CHIP by orthogonal ubiquitin transfer.Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor.Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signatureDerailing the UPS of Protein Turnover in Cancer and other Human Diseases
P2860
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P2860
c-Cbl, a ubiquitin E3 ligase that targets active β-catenin: a novel layer of Wnt signaling regulation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@ast
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@en
type
label
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@ast
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@en
prefLabel
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@ast
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@en
P2093
P2860
P50
P356
P1476
c-Cbl, a ubiquitin E3 ligase t ...... r of Wnt signaling regulation.
@en
P2093
Elazer Edelman
Rosana Meyer
Sowmya Shivanna
P2860
P304
23505-23517
P356
10.1074/JBC.M113.473801
P407
P577
2013-06-06T00:00:00Z