The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation
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Neuronal Mitophagy in Neurodegenerative DiseasesPINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease.Food restriction increase the expression of mTORC1 complex genes in the skeletal muscle of juvenile pacu (Piaractus mesopotamicus).Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system.Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.Molecular Functions of Glycoconjugates in Autophagy.Cardiac ubiquitin ligases: Their role in cardiac metabolism, autophagy, cardioprotection and therapeutic potential.Ubiquitin recognition by the proteasome.The Roles of SUMO in Metabolic Regulation.Ubiquitin enzymes in the regulation of immune responses.Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy.Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation.Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway.Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.Stable Isotope Labeling Reveals Novel Insights Into Ubiquitin-Mediated Protein Aggregation With Age, Calorie Restriction, and Rapamycin Treatment.Mammalian mitophagy - from in vitro molecules to in vivo models.Knockdown of the mitochondria-localized protein p13 protects against experimental parkinsonism.Mechanisms and Physiological Roles of Mitophagy in Yeast.Post-translational modifications: How to modulate Rab7 functions.Structural basis for specific cleavage of Lys6-linked polyubiquitin chains by USP30.Investigation of Yeast Mitophagy with Fluorescence Microscopy and Western Blotting.Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.Endosomal Rab cycles regulate Parkin-mediated mitophagy.In-cell NMR: from metabolites to macromolecules.The IAP family member BRUCE regulates autophagosome-lysosome fusion.PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol.The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans.Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats.Unexpected mitochondrial matrix localization of Parkinson's disease-related DJ-1 mutants but not wild-type DJ-1.Comparative analysis of Parkinson's disease-associated genes reveals altered survival and bioenergetics of parkin-deficient dopamine neurons in mice.Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin.Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss.HUWE1 E3 ligase promotes PINK1/PARKIN-independent mitophagy by regulating AMBRA1 activation via IKKα
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P2860
The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The ubiquitin signal and autop ...... g to mitochondrial degradation
@ast
The ubiquitin signal and autop ...... g to mitochondrial degradation
@en
type
label
The ubiquitin signal and autop ...... g to mitochondrial degradation
@ast
The ubiquitin signal and autop ...... g to mitochondrial degradation
@en
prefLabel
The ubiquitin signal and autop ...... g to mitochondrial degradation
@ast
The ubiquitin signal and autop ...... g to mitochondrial degradation
@en
P2860
P356
P1433
P1476
The ubiquitin signal and autop ...... g to mitochondrial degradation
@en
P2093
Keiji Tanaka
Koji Yamano
P2860
P304
P356
10.15252/EMBR.201541486
P577
2016-02-08T00:00:00Z