DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking - Wikidata - wikimedia - TriplyDB

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

http://www.wikidata.org/entity/Q36637260

about

Nucleic Acid sensors and type I interferon production in systemic lupus erythematosus DNA Damage Response and Immune Defense: Links and Mechanisms Stress Beyond Translation: Poxviruses and More STING: infection, inflammation and cancer Evasion of host antiviral innate immunity by HSV-1, an update DNA Damage: From Chronic Inflammation to Age-Related Deterioration Innate immune recognition of DNA: A recent history International Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and disease Bacterial recognition pathways that lead to inflammasome activation RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms Molecular mechanisms for enhanced DNA vaccine immunogenicity.Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency RAD51 interconnects between DNA replication, DNA repair and immunity.Involvement of GATA1 and Sp3 in the activation of the murine STING gene promoter in NIH3T3 cells.Interferons and their stimulated genes in the tumor microenvironment Activated STING in a vascular and pulmonary syndrome Intracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogens Sweeten PAMPs: Role of Sugar Complexed PAMPs in Innate Immunity and Vaccine Biology.Listeria monocytogenes dampens the DNA damage response The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection.Interplay between DNA repair and inflammation, and the link to cancer A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus.Interferon regulatory factors: critical mediators of human lupus.Cell type-specific subcellular localization of phospho-TBK1 in response to cytoplasmic viral DNA A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant.cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection.What's the damage? The impact of pathogens on pathways that maintain host genome integrity Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome.ER Adaptor SCAP Translocates and Recruits IRF3 to Perinuclear Microsome Induced by Cytosolic Microbial DNAs.The E3 ubiquitin ligase RNF185 facilitates the cGAS-mediated innate immune response.Cytosolic DNA Sensor Upregulation Accompanies DNA Electrotransfer in B16.F10 Melanoma Cells MAP4-regulated dynein-dependent trafficking of BTN3A1 controls the TBK1-IRF3 signaling axis.Recognition of herpes simplex viruses: toll-like receptors and beyond Type I interferons induced by radiation therapy mediate recruitment and effector function of CD8(+) T cells Gene Deletion in Barley Mediated by LTR-retrotransposon BARE.Promising Targets for Cancer Immunotherapy: TLRs, RLRs, and STING-Mediated Innate Immune Pathways Mechanisms of transcriptional activation of the stimulator of interferon genes by transcription factors CREB and c-Myc.Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents.Multifaceted roles of TRIM38 in innate immune and inflammatory responses.Immune sensing of DNA

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DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

http://www.wikidata.org/entity/Q36637260

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2013 nî lūn-bûn

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DNA damage sensor MRE11 recogn ...... y regulating STING trafficking

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DNA damage sensor MRE11 recogn ...... y regulating STING trafficking

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DNA damage sensor MRE11 recogn ...... y regulating STING trafficking

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P1476

DNA damage sensor MRE11 recogn ...... y regulating STING trafficking

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P2093

Glen N Barber

http://www.w3.org/2001/XMLSchema#string

Junya Kobayashi

http://www.w3.org/2001/XMLSchema#string

Kenshi Komatsu

http://www.w3.org/2001/XMLSchema#string

Kenta Maruyama

http://www.w3.org/2001/XMLSchema#string

Takeshi Kondo

http://www.w3.org/2001/XMLSchema#string

Taro Kawai

http://www.w3.org/2001/XMLSchema#string

Tatsuya Saitoh

http://www.w3.org/2001/XMLSchema#string

P2860

RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control

A Toll-like receptor recognizes bacterial DNA

IFI16 is an innate immune sensor for intracellular DNA

IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection

RINT-1 regulates the localization and entry of ZW10 to the syntaxin 18 complex

RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

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3581880

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