Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal.
about
Caspase Exploitation by Legionella pneumophilaType IV secretion system of Brucella spp. and its effectorsRegulation of bacterial virulence by Csr (Rsm) systemsA type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytateThe Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling.Purification and proteomics of pathogen-modified vacuoles and membranesUbiquitination independent of E1 and E2 enzymes by bacterial effectorsIdentification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic high-content screeningLegionella pneumophila utilizes a single-player disulfide-bond oxidoreductase system to manage disulfide bond formation and isomerizationLegionella pneumophila prevents proliferation of its natural host Acanthamoeba castellanii.Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells.Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetiiIdentification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway.The Legionella longbeachae Icm/Dot substrate SidC selectively binds phosphatidylinositol 4-phosphate with nanomolar affinity and promotes pathogen vacuole-endoplasmic reticulum interactions.Reassessing the role of DotF in the Legionella pneumophila type IV secretion systemCoxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication.Sensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infectionA screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesisLpg0393 of Legionella pneumophila is a guanine-nucleotide exchange factor for Rab5, Rab21 and Rab22.Intragenic recombination has a critical role on the evolution of Legionella pneumophila virulence-related effector sidJThe Legionella pneumophila effector protein, LegC7, alters yeast endosomal trafficking.Toxicity and SidJ-Mediated Suppression of Toxicity Require Distinct Regions in the SidE Family of Legionella pneumophila EffectorsA new way to detect the danger: Lysosomal cell death induced by a bacterial ribosomal protein.Endoplasmic Reticulum Tubule Protein Reticulon 4 Associates with the Legionella pneumophila Vacuole and with Translocated Substrate Ceg9.Molecular Characterization of LubX: Functional Divergence of the U-Box Fold by Legionella pneumophila.Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence FactorBeyond Rab GTPases Legionella activates the small GTPase Ran to promote microtubule polymerization, pathogen vacuole motility, and infectionThe Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetiiBiogenesis of the lysosome-derived vacuole containing Coxiella burnetii.Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA.Legionella pneumophila strain associated with the first evidence of person-to-person transmission of Legionnaires' disease: a unique mosaic genetic backbone.Refining the plasmid-encoded type IV secretion system substrate repertoire of Coxiella burnetii.Implication of the VirD4 coupling protein of the Lvh type 4 secretion system in virulence phenotypes of Legionella pneumophilaEffector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole.Poison domains block transit of translocated substrates via the Legionella pneumophila Icm/Dot systemCoxiella burnetii effector CvpB modulates phosphoinositide metabolism for optimal vacuole development.LtpD is a novel Legionella pneumophila effector that binds phosphatidylinositol 3-phosphate and inositol monophosphatase IMPA1.Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires.Coxiella burnetii effector protein subverts clathrin-mediated vesicular trafficking for pathogen vacuole biogenesis.
P2860
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P2860
Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Computational modeling and exp ...... ted type-IVB secretion signal.
@ast
Computational modeling and exp ...... ted type-IVB secretion signal.
@en
type
label
Computational modeling and exp ...... ted type-IVB secretion signal.
@ast
Computational modeling and exp ...... ted type-IVB secretion signal.
@en
prefLabel
Computational modeling and exp ...... ted type-IVB secretion signal.
@ast
Computational modeling and exp ...... ted type-IVB secretion signal.
@en
P2093
P2860
P50
P356
P1476
Computational modeling and exp ...... ted type-IVB secretion signal.
@en
P2093
Howard A Shuman
Kierstyn Schwartz
Tal Zusman
Ziv Lifshitz
P2860
P304
P356
10.1073/PNAS.1215278110
P407
P577
2013-02-04T00:00:00Z