Mapping of a major surface-exposed site in herpes simplex virus protein Vmw65 to a region of direct interaction in a transcription complex assembly
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Mutations in host cell factor 1 separate its role in cell proliferation from recruitment of VP16 and LZIPThe novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABPZhangfei: a second cellular protein interacts with herpes simplex virus accessory factor HCF in a manner similar to Luman and VP16.Luman, a new member of the CREB/ATF family, binds to herpes simplex virus VP16-associated host cellular factorThe herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCFCrystal structure of the conserved core of the herpes simplex virus transcriptional regulatory protein VP16Viral mimicry: common mode of association with HCF by VP16 and the cellular protein LZIPInterdigitated residues within a small region of VP16 interact with Oct-1, HCF, and DNATruncation of the C-terminal acidic transcriptional activation domain of herpes simplex virus VP16 renders expression of the immediate-early genes almost entirely dependent on ICP0Varicella-zoster virus open reading frame 10 is a virulence determinant in skin cells but not in T cells in vivoICP0 is not required for efficient stress-induced reactivation of herpes simplex virus type 1 from cultured quiescently infected neuronal cells.A single amino acid substitution in herpes simplex virus type 1 VP16 inhibits binding to the virion host shutoff protein and is incompatible with virus growth.Autocatalytic proteolysis of the transcription factor-coactivator C1 (HCF): a potential role for proteolytic regulation of coactivator function.VP16 interacts via its activation domain with VP22, a tegument protein of herpes simplex virus, and is relocated to a novel macromolecular assembly in coexpressing cells.The Epstein-Barr virus immortalizing protein EBNA-2 is targeted to DNA by a cellular enhancer-binding protein.Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhsThe bovine herpesvirus alpha gene trans-inducing factor activates transcription by mechanisms different from those of its herpes simplex virus type 1 counterpart VP16.Mutation of the Oct-1 POU-specific recognition helix leads to altered DNA binding and influences enhancement of adenovirus DNA replication.EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1.Protein and DNA elements involved in transactivation of the promoter of the bovine herpesvirus (BHV) 1 IE-1 transcription unit by the BHV alpha gene trans-inducing factorTranscriptional activation by herpes simplex virus type 1 VP16 in vitro and its inhibition by oligopeptides.A trans-acting peptide activates the yeast a1 repressor by raising its DNA-binding affinity.Differences in determinants required for complex formation and transactivation in related VP16 proteins.Tetracycline-controlled transcription in eukaryotes: novel transactivators with graded transactivation potential.Protein interactions in the herpes simplex virus type 1 VP16-induced complex: VP16 peptide inhibition and mutational analysis of host cell factor requirements.Repression of gene expression upon infection of cells with herpes simplex virus type 1 mutants impaired for immediate-early protein synthesis.Complex architecture of major histocompatibility complex class II promoters: reiterated motifs and conserved protein-protein interactionsConcerted activity of host cell factor subregions in promoting stable VP16 complex assembly and preventing interference by the acidic activation domain.The extreme carboxyl terminus of the equine herpesvirus 1 homolog of herpes simplex virus VP16 is essential for immediate-early gene activation.
P2860
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P2860
Mapping of a major surface-exposed site in herpes simplex virus protein Vmw65 to a region of direct interaction in a transcription complex assembly
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1993 nî lūn-bûn
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1993年の論文
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1993年論文
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1993年論文
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1993年論文
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1993年論文
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1993年論文
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1993年论文
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1993年论文
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1993年论文
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name
Mapping of a major surface-exp ...... transcription complex assembly
@ast
Mapping of a major surface-exp ...... transcription complex assembly
@en
type
label
Mapping of a major surface-exp ...... transcription complex assembly
@ast
Mapping of a major surface-exp ...... transcription complex assembly
@en
prefLabel
Mapping of a major surface-exp ...... transcription complex assembly
@ast
Mapping of a major surface-exp ...... transcription complex assembly
@en
P2860
P1433
P1476
Mapping of a major surface-exp ...... transcription complex assembly
@en
P2093
P2860
P304
P407
P577
1993-02-01T00:00:00Z