Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.
about
Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable ResistanceFlipping the switch: tools for detecting small molecule inhibitors of staphylococcal virulence.Norlichexanthone Reduces Virulence Gene Expression and Biofilm Formation in Staphylococcus aureusRgg-associated SHP signaling peptides mediate cross-talk in StreptococciSelective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistanceChemical and thermal unfolding of a global staphylococcal virulence regulator with a flexible C-terminal endFunctional reconstitution of Staphylococcus aureus truncated AgrC histidine kinase in a model membrane system.VLP-based vaccine induces immune control of Staphylococcus aureus virulence regulation.Autoinducer-2 plays a crucial role in gut colonization and probiotic functionality of Bifidobacterium breve UCC2003.Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry.Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase.Staphylococcus epidermidis agr quorum-sensing system: signal identification, cross talk, and importance in colonization.Targeting Staphylococcus aureus quorum sensing with nonpeptidic small molecule inhibitors.Colostrum hexasaccharide, a novel Staphylococcus aureus quorum-sensing inhibitor.A Surfactant-Induced Functional Modulation of a Global Virulence Regulator from Staphylococcus aureus.Screening a Commercial Library of Pharmacologically Active Small Molecules against Staphylococcus aureus BiofilmsVirulence Inhibitors from Brazilian Peppertree Block Quorum Sensing and Abate Dermonecrosis in Skin Infection ModelsIn Vitro Screening of an FDA-Approved Library Against ESKAPE Pathogens.Characterization of structural elements in native autoinducing peptides and non-native analogues that permit the differential modulation of AgrC-type quorum sensing receptors in Staphylococcus aureus.Impact of Environmental Cues on Staphylococcal Quorum Sensing and Biofilm Development.Highly Stable, Amide-Bridged Autoinducing Peptide Analogues that Strongly Inhibit the AgrC Quorum Sensing Receptor in Staphylococcus aureus.Structural characterization of native autoinducing peptides and abiotic analogues reveals key features essential for activation and inhibition of an AgrC quorum sensing receptor in Staphylococcus aureus.Prevention and treatment of Staphylococcus aureus biofilms.Targeting agr- and agr-Like quorum sensing systems for development of common therapeutics to treat multiple gram-positive bacterial infections.Novel approaches for the design and discovery of quorum-sensing inhibitors.Defining motility in the Staphylococci.Regulation of Virulence in Staphylococcus aureus: Molecular Mechanisms and Remaining Puzzles.Quorum Quenching Strategy Targeting Gram-Positive Pathogenic Bacteria.Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria.Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy To Target Antibiotic-Resistant Infections.Structure-Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross-group ComD Receptor Activation.Rationale design of quorum-quenching peptides that target the VirSR system of Clostridium perfringens.Truncated Autoinducing Peptides as Antagonists of Staphylococcus lugdunensis Quorum Sensing.Transcriptional downregulation of agr expression in Staphylococcus aureus during growth in human serum can be overcome by constitutively active mutant forms of the sensor kinase AgrC.Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing.Small-molecule quorum quenchers to prevent Staphylococcus aureus infection.Efficient and Scalable Precision Genome Editing in Staphylococcus aureus through Conditional Recombineering and CRISPR/Cas9-Mediated Counterselection.Detection of Agr-Type Autoinducing Peptides Produced by Staphylococcus aureus.N-Methyl and peptoid scans of an autoinducing peptide reveal new structural features required for inhibition and activation of AgrC quorum sensing receptors in Staphylococcus aureus.Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity
P2860
Q21089631-AA4E87E2-B9B7-44D3-B099-6DEB6F22065BQ27692092-B51228AB-522B-4D62-ABEE-9B84874A7CE9Q28354141-77B6DB9D-499D-48A1-8417-67A1B5BC632AQ28533785-87FDD137-3105-4B1D-9215-F2C67F357ECEQ28539668-11B52FA8-3675-4919-9AA0-A52ED8DDC533Q28545169-0217BE22-4FEA-4FB7-88AB-B27072E3F068Q30356353-CCC14BE3-A28D-4FED-9033-3913F3ED5188Q33677615-389CF464-0CAA-4713-BD98-4A9FF9E74EAFQ33679660-AD7FA316-7AC1-4852-8139-EC84D86989DDQ33815668-046CA78D-9378-4FBB-9957-38A337D665AEQ34218098-41EE3885-7A45-441D-AEC5-21D518E9A394Q34297761-59C9F02C-94FA-4FF5-B226-52E34DE0B773Q35110055-57E44B92-A112-46C9-B756-3B71746C7520Q35169061-9ABF31A0-1B72-4BA3-B598-78CCDE1A3123Q35962130-40A60571-D8A2-4D58-9808-2E8B8E956855Q36073174-C62FB7A5-D095-4A60-BAE7-4D35D17B2EFCQ36276699-73E54E11-60E2-4427-A664-EC04429DA532Q36278065-4F14B2C5-6F4E-46EC-8FE0-6B45FFC6560BQ36378301-D72DB504-A966-42AD-8EB7-682CCCAE121AQ37066456-80A797FC-96E1-4BA9-BBCF-D3BCC138DCB1Q37149488-2A97FB74-6FC7-442A-9634-024E78B76995Q37460586-1262CD3B-EB91-4987-A0C7-FE7FC48D536BQ37482155-13567DCD-3737-4E6E-95AC-622784F4BBFFQ38100055-E843029B-7E47-4465-886B-86FC401BE97EQ38193593-0A87EA22-8999-4363-B7B3-F847390703CCQ38734889-AF62E018-E0AE-4F9F-A43F-2CA29FEBD80EQ38772517-7D91A564-DC06-41CE-AB4E-666986F604B9Q38831839-20DEB681-93BC-43EF-B86E-995CFF0CE9CAQ38856105-6098CBBC-5A80-4BCA-8469-636BBF59C83AQ40175211-C07B681F-1794-46EE-BE33-31FE26B462F7Q40324040-AAB2C45E-299E-43DC-94DB-A8E14C05F340Q40458848-B22B4A68-5398-4E37-88D6-C3809F2C20AEQ40554825-172F12CB-4B89-4303-9D4C-88968D3A335CQ42162480-BBF9A2F4-263F-4339-9BDD-096D049D3803Q46249180-331D8059-2D3C-4BBF-8168-BB0AA18E9E0DQ46346671-76D26E02-7063-4F4E-B343-B80308C6C5B5Q49791101-F5EC1C11-0AF3-4C4D-AE6E-C3BD130423BFQ50053304-280EA182-580E-4D47-BD20-95A603558F64Q54378658-2BA7DE01-1493-4C47-A37F-A48B471202F4Q58200362-45565DF0-BF13-4C3B-8609-1EF087D9A50C
P2860
Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Attenuating Staphylococcus aur ...... dicinal chemistry perspective.
@ast
Attenuating Staphylococcus aur ...... dicinal chemistry perspective.
@en
type
label
Attenuating Staphylococcus aur ...... dicinal chemistry perspective.
@ast
Attenuating Staphylococcus aur ...... dicinal chemistry perspective.
@en
prefLabel
Attenuating Staphylococcus aur ...... dicinal chemistry perspective.
@ast
Attenuating Staphylococcus aur ...... dicinal chemistry perspective.
@en
P2860
P50
P356
P1476
Attenuating Staphylococcus aur ...... edicinal chemistry perspective
@en
P2093
Paul Williams
Weng C Chan
P2860
P304
P356
10.1021/JM3014635
P407
P577
2013-01-22T00:00:00Z