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CMV and Immunosenescence: from basics to clinics.

CMV and Immunosenescence: from basics to clinics.

http://www.wikidata.org/entity/Q36649207

about

Human T cell aging and the impact of persistent viral infections Clinical immune-monitoring strategies for predicting infection risk in solid organ transplantation Cell-mediated immunity to human CMV infection: a brief overview Cytomegalovirus infection enhances the immune response to influenza.Differential Effect of Cytomegalovirus Infection with Age on the Expression of CD57, CD300a, and CD161 on T-Cell Subpopulations.Better immunity in later life: a position paper.Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories.The 21st century epidemic: infections as inductors of neuro-degeneration associated with Alzheimer's Disease.Decreased proportion of cytomegalovirus specific CD8 T-cells but no signs of general immunosenescence in Alzheimer's disease.CMV latent infection improves CD8+ T response to SEB due to expansion of polyfunctional CD57+ cells in young individuals.Effect of cytomegalovirus co-infection on normalization of selected T-cell subsets in children with perinatally acquired HIV infection treated with combination antiretroviral therapy.Immunosenescence of the CD8(+) T cell compartment is associated with HIV-infection, but only weakly reflects age-related processes of adipose tissue, metabolism, and muscle in antiretroviral therapy-treated HIV-infected patients and controls.The immunological footprint of CMV in HIV-1 patients stable on long-term ART IFNγ⁻TNFα⁻IL2⁻MIP1α⁻CD107a⁺PRF1⁺ CD8 pp65-Specific T-Cell Response Is Independently Associated With Time to Death in Elderly Humans Priorities for CMV vaccine development Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size.CMV seropositivity and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study Immunosenescence and gender: a study in healthy Cubans.Premature aging and immune senescence in HIV-infected children.Cytomegalovirus as a cause of hypertensive anterior uveitis in immunocompetent patients.Inflammatory and immune markers associated with physical frailty syndrome: findings from Singapore longitudinal aging studies Functional Diversity of Cytomegalovirus-Specific T Cells Is Maintained in Older People and Significantly Associated With Protein Specificity and Response Size.Perturbations of the CD8(+) T-cell repertoire in CVID patients with complications.Differential activation of CD57-defined natural killer cell subsets during recall responses to vaccine antigens.Preventing or reversing immunosenescence: can exercise be an immunotherapy?From "truly naïve" to "exhausted senescent" T cells: when markers predict functionality.Quantification of cytomegalovirus viral load.Impact of HCMV Infection on NK Cell Development and Function after HSCT.Inflammatory co-morbidities in HIV+ individuals: learning lessons from healthy ageing.NK Cell Subset Redistribution during the Course of Viral Infections.Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians.Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection.Increased IL-15 Production and Accumulation of Highly Differentiated CD8+ Effector/Memory T Cells in the Bone Marrow of Persons with Cytomegalovirus.Effect of Cytomegalovirus (CMV) and Ageing on T-Bet and Eomes Expression on T-Cell Subsets.Effect of CMV and Aging on the Differential Expression of CD300a, CD161, T-bet, and Eomes on NK Cell Subsets.Factors related to the development of CMV-specific CD8+ T cell response in CMV-seropositive solid organ transplant candidates.Persistent infections, immune-senescence and Alzheimer's disease.Association between γ marker, human leucocyte antigens and killer immunoglobulin-like receptors and the natural course of human cytomegalovirus infection: a pilot study performed in a Sicilian population.5(th) International Workshop on CMV and Immunosenescence - A shadow of cytomegalovirus infection on immunological memory.Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

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CMV and Immunosenescence: from basics to clinics.

http://www.wikidata.org/entity/Q36649207

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2012年论文

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2012年论文

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2012年论文

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CMV and Immunosenescence: from basics to clinics.

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Immunity and Ageing

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CMV and Immunosenescence: from basics to clinics.

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Allison E Aiello

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Anis Larbi

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Ann Hill

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Elissaveta Naumova

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George C Wang

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Janet E McElhaney

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P2860

Seropositivity to cytomegalovirus, inflammation, all-cause and cardiovascular disease-related mortality in the United States.

Cytomegalovirus antibody levels, inflammation, and mortality among elderly Latinos over 9 years of follow-up.

Evaluating cellular polyfunctionality with a novel polyfunctionality index.

Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging.

Report from the second cytomegalovirus and immunosenescence workshop.

Polyfunctional T cells accumulate in large human cytomegalovirus-specific T cell responses.

The immunoregulatory effects of CMV-infection in human fibroblasts and the impact on cellular senescence.

Cytomegalovirus seropositivity is associated with glucose regulation in the oldest old. Results from the Leiden 85-plus Study.

Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

Lifelong persistent viral infection alters the naive T cell pool, impairing CD8 T cell immunity in late life.

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Beatrix Grubeck-Loebenstein

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Janko Nikolich-Žugich

Luka Cicin-Sain

Evelyna Derhovanessian

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2012-10-31T00:00:00Z

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