The Glycine-Alanine Dipeptide Repeat from C9orf72 Hexanucleotide Expansions Forms Toxic Amyloids Possessing Cell-to-Cell Transmission Properties
about
There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALSC9orf72's Interaction with Rab GTPases-Modulation of Membrane Traffic and AutophagyCytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity.The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the ProteasomeThe small heat shock protein B8 (HSPB8) efficiently removes aggregating species of dipeptides produced in C9ORF72-related neurodegenerative diseases.Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells.Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene.The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD.Cell-to-Cell Transmission of Dipeptide Repeat Proteins Linked to C9orf72-ALS/FTD.Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteinsMIF inhibits the formation and toxicity of misfolded SOD1 amyloid aggregates: implications for familial ALS.Unraveling the Role of RNA Mediated Toxicity of C9orf72 Repeats in C9-FTD/ALS.In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
P2860
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P2860
The Glycine-Alanine Dipeptide Repeat from C9orf72 Hexanucleotide Expansions Forms Toxic Amyloids Possessing Cell-to-Cell Transmission Properties
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@ast
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@en
type
label
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@ast
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@en
prefLabel
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@ast
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@en
P2093
P2860
P356
P1476
The Glycine-Alanine Dipeptide ...... o-Cell Transmission Properties
@en
P2093
Ing-Shouh Hwang
U-Ser Jeng
Ya-Ling Chiang
Yu-Jen Chang
P2860
P304
P356
10.1074/JBC.M115.694273
P407
P50
P577
2016-01-14T00:00:00Z