Characterization of a temperature-sensitive mutant of the UL15 open reading frame of herpes simplex virus 1
about
Novel class of thiourea compounds that inhibit herpes simplex virus type 1 DNA cleavage and encapsidation: resistance maps to the UL6 gene.Human herpesvirus 6B genome sequence: coding content and comparison with human herpesvirus 6A.Herpes simplex virus type 1 portal protein UL6 interacts with the putative terminase subunits UL15 and UL28Determination and analysis of the complete nucleotide sequence of human herpesvirusInhibition of human cytomegalovirus DNA maturation by a benzimidazole ribonucleoside is mediated through the UL89 gene productResistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growthThe UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid.Inhibition of herpes simplex virus replication by WAY-150138: assembly of capsids depleted of the portal and terminase proteins involved in DNA encapsidationHerpes simplex virus capsid structure: DNA packaging protein UL25 is located on the external surface of the capsid near the verticesDynamic interactions of the UL16 tegument protein with the capsid of herpes simplex virus.The product of the herpes simplex virus type 1 UL25 gene is required for encapsidation but not for cleavage of replicated viral DNA.The herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartmentsVisualizing Herpesvirus Procapsids in Living CellsEffects of charged cluster mutations on the function of herpes simplex virus type 1 UL34 protein.ATP depletion blocks herpes simplex virus DNA packaging and capsid maturationInteraction domains of the UL16 and UL21 tegument proteins of herpes simplex virus.Herpes simplex virus DNA packaging without measurable DNA synthesis.Herpes simplex virus type 1 gene UL14: phenotype of a null mutant and identification of the encoded protein.Role of the UL25 gene product in packaging DNA into the herpes simplex virus capsid: location of UL25 product in the capsid and demonstration that it binds DNA.The varicella-zoster virus portal protein is essential for cleavage and packaging of viral DNA.Distinct and separate roles for herpesvirus-conserved UL97 kinase in cytomegalovirus DNA synthesis and encapsidation.DNA cleavage and packaging proteins encoded by genes U(L)28, U(L)15, and U(L)33 of herpes simplex virus type 1 form a complex in infected cells.An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.Isolation and characterization of the herpes simplex virus 1 terminase complex.Herpes simplex virus 1 DNA packaging proteins encoded by UL6, UL15, UL17, UL28, and UL33 are located on the external surface of the viral capsid.Quantification of the DNA cleavage and packaging proteins U(L)15 and U(L)28 in A and B capsids of herpes simplex virus type 1.Point mutations in exon I of the herpes simplex virus putative terminase subunit, UL15, indicate that the most conserved residues are essential for cleavage and packaging.Putative terminase subunits of herpes simplex virus 1 form a complex in the cytoplasm and interact with portal protein in the nucleus.Assemblons: nuclear structures defined by aggregation of immature capsids and some tegument proteins of herpes simplex virus 1Characterization of ICP6::lacZ insertion mutants of the UL15 gene of herpes simplex virus type 1 reveals the translation of two proteins.Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature.Role of cellular phosphatase cdc25C in herpes simplex virus 1 replication.Characterization of mre11 loss following HSV-1 infection.The pseudorabies virus UL28 protein enters the nucleus after coexpression with the herpes simplex virus UL15 protein.Herpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect.The herpes simplex virus 1 UL15 gene encodes two proteins and is required for cleavage of genomic viral DNAEpstein-Barr virus BALF3 has nuclease activity and mediates mature virion production during the lytic cycle.Sequences within the herpesvirus-conserved pac1 and pac2 motifs are required for cleavage and packaging of the murine cytomegalovirus genome.Intragenic and extragenic suppression of a mutation in herpes simplex virus 1 UL34 that affects both nuclear envelope targeting and membrane budding.
P2860
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P2860
Characterization of a temperature-sensitive mutant of the UL15 open reading frame of herpes simplex virus 1
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Characterization of a temperat ...... rame of herpes simplex virus 1
@ast
Characterization of a temperat ...... rame of herpes simplex virus 1
@en
type
label
Characterization of a temperat ...... rame of herpes simplex virus 1
@ast
Characterization of a temperat ...... rame of herpes simplex virus 1
@en
prefLabel
Characterization of a temperat ...... rame of herpes simplex virus 1
@ast
Characterization of a temperat ...... rame of herpes simplex virus 1
@en
P2860
P1433
P1476
Characterization of a temperat ...... rame of herpes simplex virus 1
@en
P2093
P2860
P304
P407
P577
1993-08-01T00:00:00Z