The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
about
Emerging Non-Canonical Functions and Regulation by p53: p53 and StemnessTargeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapyMutant p53 - Heat Shock Response Oncogenic Cooperation: A New Mechanism of Cancer Cell Survival.The p53R172H mutant does not enhance hepatocellular carcinoma development and progression.Mutant p53 Amplifies Epidermal Growth Factor Receptor Family Signaling to Promote Mammary Tumorigenesis.Gain-of-function miRNA signature by mutant p53 associates with poor cancer outcomeProlyl-isomerase Pin1 controls normal and cancer stem cells of the breast.Gossypol has anti-cancer effects by dual-targeting MDM2 and VEGF in human breast cancer.Illuminating p53 function in cancer with genetically engineered mouse models.Mutant p53 in cancer: new functions and therapeutic opportunities.The paradigm of mutant p53-expressing cancer stem cells and drug resistance.Clinical Outcomes of TP53 Mutations in Cancers.Effects of MDM2 inhibitors on vascular endothelial growth factor-mediated tumor angiogenesis in human breast cancer.HDAC inhibitor DWP0016 activates p53 transcription and acetylation to inhibit cell growth in U251 glioblastoma cells.Molecularly targeted therapies for p53-mutant cancers.A common p53 mutation (R175H) activates c-Met receptor tyrosine kinase to enhance tumor cell invasion.Histone deacetylase inhibitor sodium butyrate suppresses proliferation and promotes apoptosis in osteosarcoma cells by regulation of the MDM2-p53 signaling.p53 deficiency induces cancer stem cell pool expansion in a mouse model of triple-negative breast tumors.Clinical significance of different types of p53 gene alteration in surgically treated prostate cancer.Androgen induces G3BP2 and SUMO-mediated p53 nuclear export in prostate cancer.Plakoglobin restores tumor suppressor activity of p53R175H mutant by sequestering the oncogenic potential of β-catenin.
P2860
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P2860
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@ast
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@en
type
label
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@ast
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@en
prefLabel
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@ast
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@en
P2093
P2860
P356
P1433
P1476
The gain of function of p53 cancer mutant in promoting mammary tumorigenesis.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2012.299
P407
P577
2012-07-23T00:00:00Z