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Hypertension pharmacogenomics: in search of personalized treatment approaches

Hypertension pharmacogenomics: in search of personalized treatment approaches

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Is There a Role for Genomics in the Management of Hypertension?Increased Cardiac Workload in the Upright Posture in Men: Noninvasive Hemodynamics in Men Versus Women Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes).Personalized medicine: Genetic risk prediction of drug response.Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.Cardiovascular pharmacogenetics: a promise for genomically-guided therapy and personalized medicine.Aliskiren improves endothelium-dependent relaxation of thoracic aorta by activating PI3K/Akt/eNOS signal pathway in SHR.Replicated evidence for aminoacylase 3 and nephrin gene variations to predict antihypertensive drug responses.Personalized medicine-a modern approach for the diagnosis and management of hypertension.Pharmacogenetics in Cardiovascular Medicine.Genetic Variants Associated With Uncontrolled Blood Pressure on Thiazide Diuretic/β-Blocker Combination Therapy in the PEAR (Pharmacogenomic Evaluation of Antihypertensive Responses) and INVEST (International Verapamil-SR Trandolapril Study) Trials.Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension.Antihypertensive therapy in pre-eclampsia: effects of plasma from nonresponsive patients on endothelial gene expression.Gene-Gene Interactions Among PRKCA, NOS3 and BDKRB2 Polymorphisms Affect the Antihypertensive Effects of Enalapril.Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene-Gene Interactions.

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P2860

Hypertension pharmacogenomics: in search of personalized treatment approaches

http://www.wikidata.org/entity/Q36652960

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2015 nî lūn-bûn

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NRNEPH.2015.176

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Nature Reviews Nephrology

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Hypertension pharmacogenomics: in search of personalized treatment approaches

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Julie A Johnson

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Rhonda M Cooper-DeHoff

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P2860

Pharmacometabolomics reveals racial differences in response to atenolol treatment

Heart Disease and Stroke Statistics--2015 Update: A Report From the American Heart Association

Effects of Blood Pressure Reduction in Mild Hypertension

Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study

Genetics of resistant hypertension: a novel pharmacogenomics phenotype

Clinical Pharmacogenetics Implementation Consortium Guidelines for CYP2C9 and VKORC1 genotypes and warfarin dosing

A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report

Polymorphisms of alpha-adducin and salt sensitivity in patients with essential hypertension

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10.1038/NRNEPH.2015.176

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pharmacogenomics

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