Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
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Clinical significance of T cell metabolic reprogramming in cancerFundamentals of cancer metabolismMetabolic rewiring in melanomaAntioxidant Activity during Tumor Progression: A Necessity for the Survival of Cancer Cells?TRAF3 deficiency promotes metabolic reprogramming in B cellsNADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting "stemness".Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge.Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and Epigenetics.The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?Anti-cancer effects of vitamin C revisited.sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistanceSynergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity.Determination of GLUT1 Oligomerization Parameters using Bioluminescent Förster Resonance Energy Transfer.Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine.Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.Ascorbate availability affects tumor implantation-take rate and increases tumor rejection in Gulo-/- mice.Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy.Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer.A historic study that opened a new chapter in nutritional scienceTriethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer CellAir pollution and DNA methylation alterations in lung cancer: A systematic and comparative study.Glucose transporter GLUT1 expression and clinical outcome in solid tumors: a systematic review and meta-analysis.Opposing effects of low versus high concentrations of water soluble vitamins/dietary ingredients Vitamin C and niacin on colon cancer stem cells (CSCs).O2⋅- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate.Targeting metabolic reprogramming in KRAS-driven cancers.Vitamin C: the known and the unknown and Goldilocks.Cellular and molecular aspects of pancreatic cancer.Vitamin C in synergism with cisplatin induces cell death in cervical cancer cells through altered redox cycling and p53 upregulation.Metabolomics: A Primer.Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis.Mitochondria and Cancer.Ascorbic acid intake and oxalate synthesisSodium ascorbate kills Candida albicans in vitro via iron-catalyzed Fenton reaction: importance of oxygenation and metabolism.Monitoring cancer prognosis, diagnosis and treatment efficacy using metabolomics and lipidomics.Dual targeting of the thioredoxin and glutathione systems in cancer and HIV.High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro.Novel insights into redox system and the mechanism of redox regulation.Caffeine inhibition of GLUT1 is dependent on the activation state of the transporter.Parkin and mitophagy in cancer.
P2860
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P2860
Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@ast
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@en
type
label
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@ast
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@en
prefLabel
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@ast
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@en
P2093
P2860
P50
P356
P1433
P1476
Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.
@en
P2093
Adam Kavalier
Ashlesha Muley
Carlo Rago
Changyuan Lu
Darryl J Pappin
Edouard Mullarky
Eugenia G Giannopoulou
Iok In Christine Chio
Jihye Paik
P2860
P304
P356
10.1126/SCIENCE.AAA5004
P407
P577
2015-11-05T00:00:00Z