Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. - Wikidata - wikimedia - TriplyDB

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

http://www.wikidata.org/entity/Q36653423

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Clinical significance of T cell metabolic reprogramming in cancer Fundamentals of cancer metabolism Metabolic rewiring in melanoma Antioxidant Activity during Tumor Progression: A Necessity for the Survival of Cancer Cells?TRAF3 deficiency promotes metabolic reprogramming in B cells NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting "stemness".Vitamin C Transporters in Cancer: Current Understanding and Gaps in Knowledge.Vitamin C in Stem Cell Biology: Impact on Extracellular Matrix Homeostasis and Epigenetics.The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition.Reprogramming glucose metabolism in cancer: can it be exploited for cancer therapy?Anti-cancer effects of vitamin C revisited.sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance Synergistic effects of ascorbate and sorafenib in hepatocellular carcinoma: New insights into ascorbate cytotoxicity.Determination of GLUT1 Oligomerization Parameters using Bioluminescent Förster Resonance Energy Transfer.Vitamin C increases viral mimicry induced by 5-aza-2'-deoxycytidine.Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.Ascorbate availability affects tumor implantation-take rate and increases tumor rejection in Gulo-/- mice.Tumor cells have decreased ability to metabolize H2O2: Implications for pharmacological ascorbate in cancer therapy.Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer.A historic study that opened a new chapter in nutritional science Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study.Glucose transporter GLUT1 expression and clinical outcome in solid tumors: a systematic review and meta-analysis.Opposing effects of low versus high concentrations of water soluble vitamins/dietary ingredients Vitamin C and niacin on colon cancer stem cells (CSCs).O2⋅- and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate.Targeting metabolic reprogramming in KRAS-driven cancers.Vitamin C: the known and the unknown and Goldilocks.Cellular and molecular aspects of pancreatic cancer.Vitamin C in synergism with cisplatin induces cell death in cervical cancer cells through altered redox cycling and p53 upregulation.Metabolomics: A Primer.Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis.Mitochondria and Cancer.Ascorbic acid intake and oxalate synthesis Sodium ascorbate kills Candida albicans in vitro via iron-catalyzed Fenton reaction: importance of oxygenation and metabolism.Monitoring cancer prognosis, diagnosis and treatment efficacy using metabolomics and lipidomics.Dual targeting of the thioredoxin and glutathione systems in cancer and HIV.High-dose ascorbate and arsenic trioxide selectively kill acute myeloid leukemia and acute promyelocytic leukemia blasts in vitro.Novel insights into redox system and the mechanism of redox regulation.Caffeine inhibition of GLUT1 is dependent on the activation state of the transporter.Parkin and mitophagy in cancer.

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P2860

Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH.

http://www.wikidata.org/entity/Q36653423

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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name

Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

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Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

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Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

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Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

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Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

@ast

Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

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Vitamin C selectively kills KR ...... ncer cells by targeting GAPDH.

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Adam Kavalier

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Ashlesha Muley

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Carlo Rago

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Changyuan Lu

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Darryl J Pappin

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Edouard Mullarky

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Eugenia G Giannopoulou

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Iok In Christine Chio

http://www.w3.org/2001/XMLSchema#string

Jihye Paik

http://www.w3.org/2001/XMLSchema#string

Jihye Yun

http://www.w3.org/2001/XMLSchema#string

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Adenomatous polyposis coli (APC) is required for normal development of skin and thymus

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.

Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance

Supplemental ascorbate in the supportive treatment of cancer: reevaluation of prolongation of survival times in terminal human cancer

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1391-1396

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10.1126/SCIENCE.AAA5004

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6266

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350

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Lewis C. Cantley

Olivier Elemento

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2015-11-05T00:00:00Z

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283545002

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26541605

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colorectal cancer

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4778961

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