Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.

Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.

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http://www.wikidata.org/entity/Q36655158
Engineering therapeutic protein disaggregases.The epichaperome is an integrated chaperome network that facilitates tumour survivalModulation of Molecular Chaperones in Huntington's Disease and Other Polyglutamine Disorders.Chaperones rescue the energetic landscape of mutant CFTR at single molecule and in cell.The epichaperome: the power of many as the power of one.Proteomic interrogation of HSP90 and insights for medical research.Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models.Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma.HSP90 stabilizes B-cell receptor kinases in a multi-client interactome: PU-H71 induces CLL apoptosis in a cytoprotective microenvironment.Triptolide, a HSP90 middle domain inhibitor, induces apoptosis in triple manner.Rapid labelling and covalent inhibition of intracellular native proteins using ligand-directed N-acyl-N-alkyl sulfonamide.Structures of ubiquitin-like (Ubl) and Hsp90-like domains of sacsin provide insight into pathological mutationsHSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neuronsBlocking nuclear export of HSPA8 after heat shock stress severely alters cell survival
P2860

Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.

Item
http://www.wikidata.org/entity/Q36655158
description
2016 nî lūn-bûn
@nan
2016 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
name
Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@ast
Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@en
type
label
Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@ast
Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@en
prefLabel
Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@ast
Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@en
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Chemical Tools to Investigate Mechanisms Associated with HSP90 and HSP70 in Disease.
@en
P2093
P2860
P304
P31
P356
10.1016/J.CHEMBIOL.2015.12.006
P433
P478
P50
P577
P698
P932